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Fibromyalgia and Circadian Blood Pressure

NCT05113589 NA COMPLETED

Fibromyalgia syndrome (FMS) is a chronic and multicomponent illness with unknown etiology and is considered the most frequent cause of diffuse chronic musculoskeletal pain. There is little evidence to confirm if the condition is fully improved after a specific treatment program. Thus a multifactorial understanding of the pathology is crucial to propose new alternative treatments. In this regard, an alteration in circadian blood pressure and persistent nocturnal sympathetic hyperactivity have been shown in patients suffering from fibromyalgia syndrome, leading to malfunctioning in the autonomic nervous system. This is a common pathogenesis shared also by patients with non-dipping blood pressure pattern, which has been closely associated with cardiovascular morbidity. Finally, a significant relationship between fibromyalgia syndrome and non-dipping blood pressure pattern has been shown. Therefore, alterations in circadian blood pressure appear as an additional risk factor in patients with fibromyalgia syndrome, and treatments focus on recovering such blood pressure pattern may be indicated.

Details

Lead sponsorUniversity of Malaga
PhaseNA
StatusCOMPLETED
Enrolment40
Start dateMon Feb 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time)
CompletionFri Jul 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Interventions

Countries

Spain