Adults 21 to 75, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Mean Change in Electric Current Subjects Indicated They Could Hear a Tone at Certain FrequenciesPrimary· Baseline, approximately 2 hours
Evaluated by increasing the amplitude of the current input until the subject could hear a tone at 250 Hz, 500 Hz, 1,000 Hz, 2,000 Hz, 4,000 Hz, 8,000 Hz, 10,000 Hz, 12,500 Hz and 16,000 Hz. The mean electric current is reported in Milliampere (mA).
250 Hz
Group
Value
95% CI
Normal Hearing Subjects
2.16
± 1.07
Bilateral Hearing Impaired
2.88
± 1.44
Asymmetrical Hearing-impaired
2.88
± 0.97
500 Hz
Group
Value
95% CI
Normal Hearing Subjects
1.86
± 1.62
Bilateral Hearing Impaired
2.93
± 1.42
Asymmetrical Hearing-impaired
2.40
± 1.14
1,000 Hz
Group
Value
95% CI
Normal Hearing Subjects
1.09
± 0.42
Bilateral Hearing Impaired
1.75
± 0.53
Asymmetrical Hearing-impaired
1.70
± 0.42
2,000 Hz
Group
Value
95% CI
Normal Hearing Subjects
1.29
± 0.43
Bilateral Hearing Impaired
1.77
± 0.81
Asymmetrical Hearing-impaired
1.71
± 0.60
4,000 Hz
Group
Value
95% CI
Normal Hearing Subjects
1.56
± 0.67
Bilateral Hearing Impaired
3.50
± 2.35
Asymmetrical Hearing-impaired
1.84
± 0.68
8,000 Hz
Group
Value
95% CI
Normal Hearing Subjects
1.71
± 0.79
Bilateral Hearing Impaired
2.25
± 1.06
Asymmetrical Hearing-impaired
3.00
± 1.76
10,000 Hz
Group
Value
95% CI
Normal Hearing Subjects
1.97
± 1.06
Bilateral Hearing Impaired
3.25
± 1.06
Asymmetrical Hearing-impaired
3.96
± 2.51
12,500 Hz
Group
Value
95% CI
Normal Hearing Subjects
2.29
± 1.32
Bilateral Hearing Impaired
6.00
± 3.46
Asymmetrical Hearing-impaired
3.67
± 1.47
Speech Intelligibility in Quiet EnvironmentPrimary· Baseline, approximately 2 hours
Measured using the modified rhyme test (MRT) consisting of a set of 50 six-item wordlist. Each word list contains single syllable words with a consonant-vowel-consonant sound sequence. Subjects completed electrical word recognition testing in a quiet environment. Electrodes were placed at 3 unique locations (forehead, mastoid, neck) to measure how well speech could be delivered to the subject through the skin electrodes in a manner that would allow subjects to recognize words in a quiet environment. There were 2 experiments done for speech intelligibility. The first involved 20 subjects (outco
Forehead
Group
Value
95% CI
Normal Hearing Subjects
84.38
± 14.9
Mastoid
Group
Value
95% CI
Normal Hearing Subjects
94.06
± 5.9
Neck
Group
Value
95% CI
Normal Hearing Subjects
84.06
± 11.6
Speech Intelligibility in Quiet and Noisy EnvironmentsPrimary· Baseline; approximately 2 hours
Measured using the modified rhyme test (MRT) consisting of a set of 50 six-item wordlist. Each word list contains single syllable words with a consonant-vowel-consonant sound sequence. Subjects completed electrical word recognition testing in a quiet, then a noisy environment. Electrodes were placed at 3 unique locations (mastoid, wrist, back) to measure how well speech could be delivered to the subject through the skin electrodes in a manner that would allow subjects to recognize words in a quiet and noisy environment. There were 2 experiments done for speech intelligibility. The first involv
Mastoid-Quiet Environment
Group
Value
95% CI
Normal Hearing Subjects
93.86
± 8.2
Wrist-Quiet Environment
Group
Value
95% CI
Normal Hearing Subjects
93
± 9.7
Back-Quiet Environment
Group
Value
95% CI
Normal Hearing Subjects
93.83
± 10.2
Mastoid-Noisy Environment
Group
Value
95% CI
Normal Hearing Subjects
85.37
± 11.7
Wrist-Noisy Environment
Group
Value
95% CI
Normal Hearing Subjects
86
± 12.7
Back-Noisy Environment
Group
Value
95% CI
Normal Hearing Subjects
82.07
± 12.5
Sponsor's own description
The purpose of this research is to develop a portable wearable hardware headset using a computer-based software that can establish the optimal stimulation parameters appropriate for medical and consumer environments for individuals with hearing impaired and normal hearing individuals.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
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Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
Last refreshed: 30 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05112809.