Who is sponsoring NCT05111262?

NCT05111262 is sponsored by Washington University School of Medicine.

What condition does NCT05111262 study?

NCT05111262 studies Asthma, Nonadherence, Medication.

Is NCT05111262 still recruiting?

NCT05111262 is currently active, enrolled. Last updated 17 September 2025.

Last reviewed 2025-09-17 · How we verify

NCT05111262

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Symptom-driven ICS/LABA Therapy for Patients With Asthma Non-adherent to Daily Maintenance Inhalers

Active, enrolled Phase 1, PHASE2 Last updated 17 September 2025

What this trial tests

Phase 1, PHASE2 trial testing Adherence to symptom driven budesonide/formoterol as compared to adherence to maintenance ICS and symptom-driven SABA in Asthma in 60 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

16 December 2021

Primary endpoint
30 September 2025

30 November 2025

Quick facts

Lead sponsor	Washington University School of Medicine
Phase	Phase 1, PHASE2
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	other
Enrollment	60
Start date	16 December 2021
Primary completion	30 September 2025
Estimated completion	30 November 2025
Sites	1 location across United States

Drugs / interventions tested

Adherence to symptom driven budesonide/formoterol as compared to adherence to maintenance ICS and symptom-driven SABA

Conditions studied

Asthma — all drugs for Asthma →
Nonadherence, Medication — all drugs for Nonadherence, Medication →

Sponsor

Washington University School of Medicine

Who can join

Adults 12 to 75, any sex, with Asthma or Nonadherence, Medication. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Inhaler nonadherence is a common problem that has been estimated to account for approximately 60% of all asthma-related hospitalizations. Unfortunately, prior interventions to improve inhaler nonadherence have shown a lack of long-term success. This study proposes to assess the problem of non-adherence using a D\&I research lens while testing a new inhaler approach to potentially ameliorate the detrimental consequences of maintenance inhaler nonadherence.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Symptom-driven inhaled corticosteroid/long-acting beta-agonist therapy for adult patients with asthma who are non-adherent to daily maintenance inhalers: a study protocol for a pragmatic randomized controlled trial.
Krings JG, Wojcik KM, Chen V, Sekhar TC, et al · · 2022 · cited 4× · PMID 36471430 · DOI 10.1186/s13063-022-06916-3
Symptom-driven inhaled corticosteroid/long-acting beta-agonist therapy for adult patients with asthma who are non-adherent to daily maintenance inhalers: a study protocol for a pragmatic randomized-controlled trial
Krings J, Wojcik KM, Chen V, Sekhar TC, et al · · 2022 · DOI 10.21203/rs.3.rs-1746526/v1

Verify or expand the search:

Other recruiting trials for Asthma

Currently open trials in the same condition.

NCT07525375 — A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared t · Phase 2 · recruiting
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NCT07556159 — A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice · recruiting
NCT07282886 — VENTURI (VENTilation Using Respiratory Imaging) · Phase 2 · recruiting
NCT07433569 — A Study to Investigate How Budesonide and Formoterol Move Through the Body (Pharmacokinetics) When Delivered With Differ · Phase 1 · recruiting

Other Washington University School of Medicine trials

Trials by the same sponsor.

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NCT07101666 — Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer · Phase 2 · not yet recruiting
NCT07200089 — Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel) · Phase 1 · not yet recruiting
NCT07313592 — Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients · not yet recruiting
NCT07419464 — 5-Fluorouracil Response and Optimization STudy (The FROST Trial) · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05111262 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Washington University School of Medicine
Last refreshed: 17 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05111262.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing