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NCT05110469
Comparison of MgSO4 Versus Meperidine for Prevention of Shivering During Spinal Anesthesia
Phase 4 trial testing Magnesium sulfate in Shivering in 100 participants. Completed in 30 June 2021.
30 June 2021
Quick facts
| Lead sponsor | AnestesiaR |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | prevention |
| Enrollment | 100 |
| Start date | 1 February 2021 |
| Primary completion | 30 June 2021 |
| Estimated completion | 30 June 2021 |
| Sites | 1 location across Indonesia |
Drugs / interventions tested
- Magnesium sulfate — full drug profile →
- Meperidine — full drug profile →
Conditions studied
- Shivering — all drugs for Shivering →
Sponsor
AnestesiaR
Who can join
Adults 18 to 65, any sex, with Shivering. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This was a double-blind randomized interventional study of 100 patients divided into two groups. Group M received MgSO4 30 mg/kg, and group P received meperidine 0.5 mg/kg intravenously in 100 ml of 0.9% NaCl before undergoing spinal anesthesia. Participants were non-pregnant patients between 18-65 years of age, belonging to the American Society of Anesthesiologist physical status I or II. Shivering was regarded as significant if it occurred at grade 3 or 4. Data of patient characteristics, shivering degree, tympanic membrane temperature, vital sign, and side effects were recorded.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05110469
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Magnesium sulfate
Trials testing the same drug.
- NCT07524972 — Antenatal Magnesium Sulphate in High-Risk Preterm Patients · Phase 3 · recruiting
- NCT07438366 — Adding Magnesium Sulphate to Combined Pectointercostal Plane and Erector Spinae Plane Blocks for Acute and Chronic Post- · NA · not yet recruiting
- NCT07213037 — Magnesium Sulfate Versus Lidocaine as Additives to Dexmedetomidine for Cough Suppression After Functional Endoscopic Sin · Phase 3 · not yet recruiting
- NCT06979141 — Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia · Phase 3 · recruiting
- NCT07131033 — Esketamine Combined With Magnesium Sulfate for Postoperative Fatigue Syndrome in Patients Undergoing Laparoscopic Cholec · Phase 1, PHASE2 · active not recruiting
Other recruiting trials for Shivering
Currently open trials in the same condition.
- NCT07511491 — Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Cesarean Section · NA · recruiting
- NCT07489742 — Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Tonsillectomy · NA · recruiting
- NCT06708169 — Effect of Preemptive Education on the Incidence of Maternal Intraoperative Shivering in Elective Cesarean Delivery · NA · recruiting
- NCT07154849 — Comparative Study Between the Efficacy of Intravenous Hydrocortisone and Intravenous Dexmedetomidine for Prevention of P · Phase 4 · recruiting
- NCT05765162 — Safe Brain Initiative, Operationalizing Precision Anaesthesia · recruiting
Other AnestesiaR trials
Trials by the same sponsor.
- NCT03106974 — A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Obese Patients · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05110469 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by AnestesiaR
- Last refreshed: 8 November 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05110469.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing