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NCT05108597
Effect of Rectal Misoprostol in Reducing Intra-operative Blood Loss During Myomectomy
Phase 3 trial testing Misoprostol in Blood Loss, Surgical in 200 participants. Completed in 4 March 2020.
4 March 2020
Quick facts
| Lead sponsor | Pak Emirates Military Hospital |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | other |
| Enrollment | 200 |
| Start date | 4 March 2019 |
| Primary completion | 4 March 2020 |
| Estimated completion | 4 March 2020 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Misoprostol (Misoprostol) — full drug profile →
Conditions studied
- Blood Loss, Surgical — all drugs for Blood Loss, Surgical →
- Uterine Myoma — all drugs for Uterine Myoma →
Sponsor
Pak Emirates Military Hospital
Who can join
Adults 18 to 50, female only, with Blood Loss, Surgical or Uterine Myoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A total of 200 women for elective abdominal myomectomy were randomly allocated into two groups. 100 women in experimental group were administered 400ug Misoprostol (2 tablets of Prosotec®) through the rectal route prior to surgery and 100 were in control group, in which no drug was administered.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05108597
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Misoprostol
Trials testing the same drug.
- NCT07353281 — Carbetocin vs Misoprostol for Postpartum Hemorrhage Prevention · NA · not yet recruiting
- NCT06669533 — Use Misoprostol to Optimize Prevention of Cervical Cancer · NA · recruiting
- NCT07416487 — Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor · NA · completed
- NCT06765473 — Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage · Phase 3 · not yet recruiting
- NCT06452719 — Letrozole and Misoprostol for Early Pregnancy Loss Management · Phase 2 · recruiting
Other recruiting trials for Blood Loss, Surgical
Currently open trials in the same condition.
- NCT06637137 — Patient Blood Management in Patients Scheduled for Cardiac Surgery · recruiting
- NCT06725732 — Assessment of Nebulized Tranexamic Acid in Functional Endoscopic Sinus Surgery Using Modena Bleeding Score · EARLY_PHASE1 · recruiting
- NCT06428682 — Role of TXA in Patients Undergoing Breast Free Flap Reconstruction · Phase 4 · recruiting
- NCT06601582 — Effectiveness of a Intraoperative Blood Recovery System in Cardiovascular Surgery in Brazil · NA · recruiting
- NCT05077124 — Safe and Timely Antithrombotic Removal (STAR) Registry · recruiting
Other Pak Emirates Military Hospital trials
Trials by the same sponsor.
- NCT07532876 — Comparison of Elagolix and OCPs in Reducing Endometriosis Associated Pelvic Pain · Phase 4 · enrolling by invitation
- NCT07294521 — Efficacy of Platelet-rich-Fibrin Gel in Patients With Chronic Leg Ulcers · EARLY_PHASE1 · recruiting
- NCT07508098 — Comparison of Efficacy of Topical Westerhoff Formula Cream Vs Topical 4% Hydroquinone for the Treatment of Melasma · Phase 4 · completed
- NCT06602986 — Measuring the Density of Iodine in Lipiodol Depositions: Detecting an Invisible Residual Tumor After Conventional Transa · NA · not yet recruiting
- NCT06476366 — Comparison of Efficacy of Methotrexate and Azathioprine in Patients With Chronic Actinic Dermatitis: A Randomized Contro · EARLY_PHASE1 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05108597 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pak Emirates Military Hospital
- Last refreshed: 5 November 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05108597.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing