NCT05104346: AA

Presentation and Outcomes of Acute Appendicitis During COVID Pandemic

Completed NA Last updated 8 November 2021

What this trial tests

NA trial testing appendectomy in Acute Appendicitis in 1,945 participants. Completed in 1 October 2021.

Timeline

31 March 2019

Primary endpoint
31 March 2021

1 October 2021

Quick facts

Lead sponsor	Mansoura University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	1,945
Start date	31 March 2019
Primary completion	31 March 2021
Estimated completion	1 October 2021
Sites	1 location across Egypt

Drugs / interventions tested

• appendectomy

Conditions studied

• Acute Appendicitis — all drugs for Acute Appendicitis →

Sponsor

Mansoura University

Who can join

12 and older, any sex, with Acute Appendicitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute appendicitis (AA) is a frequent cause of acute abdominal pain in emergency rooms around the world \[1\]. The lifetime risk of developing AA is estimated to be about 8% \[1-3\]. The severe acute respiratory syndrome SARS-CoV-2 Coronavirus (COVID-19) pandemic has raised difficult situations for healthcare systems and organizations around the world, with direct and indirect implications for patient care delivery. COVID-19 causes a wide range of clinical symptoms, including fever, dry cough, myalgia, and exhaustion, with pulmonary involvement in many cases. According to the World Health Organization (WHO), The effect of the COVID-19 pandemic on acute appendicitis and surgical care is unknown due to a lack of evidence. To see how appendicitis care has changed as a result of the COVID-19 pandemic, this study compares clinical presentation, investigative modalities, treatment procedures, and outcomes before and after the pandemic.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Presentation and outcomes of acute appendicitis during COVID-19 pandemic: lessons learned from the Middle East-a multicentre prospective cohort study.
   El Nakeeb A, Emile SH, AbdelMawla A, Attia M, et al · · 2022 · cited 12× · PMID 35152340 · DOI 10.1007/s00384-022-04108-8