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NCT05097664

Ocular Manifestation and Related Risk Factors of Covid-19 Associated Mucormycosis: a Multicenter Study in Iran

Status unknown Last updated 28 October 2021
What this trial tests

trial in COVID-19 in 250 participants. Status unknown.

Timeline
23 August 2021
Primary endpoint
21 November 2021
20 January 2022

Quick facts

Lead sponsorIsfahan University of Medical Sciences
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment250
Start date23 August 2021
Primary completion21 November 2021
Estimated completion20 January 2022
Sites1 location across Iran

Conditions studied

Sponsor

Isfahan University of Medical Sciences

Who can join

Eligibility, any sex, with COVID-19 or Mucormycosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Coronavirus disease 2019 (COVID-19) infection caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may manifest as a variety of disease patterns, ranging from mild to life-threatening pneumonia. Mucormycosis has been suspected to cause significant morbidity in infected people since the outbreak of the COVID-19 pandemic. Individuals who require hospitalization and intensive care are more vulnerable, as they have reached an advanced stage of their disease. Investigators will discuss the major risk factors, ocular presentation, and outcome of mucormycosis in individuals infected with SARS-CoV-2 in this study. From August 2021 to January 2022, a cross-sectional descriptive multicenter investigation would be conducted on patients with biopsy-confirmed mucormycosis and RTPCR confirmed COVID19. Demographic data, the time interval between COVID19 and mucormycosis, underlying systemic disorders, clinical characteristics, disease course, and outcomes would be analyzed.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Risk Factors of COVID-19 associated mucormycosis in Iranian patients: a multicenter study.
    Eshraghi B, Khademi B, Mirmohammadkhani M, Khataminia G, et al · · 2024 · cited 8× · PMID 39174954 · DOI 10.1186/s12879-024-09755-6
  2. One-Year Patient Survival After COVID-19-Associated Rhino-Orbital-Cerebral Mucormycosis: A Multicenter Study.
    Eshraghi B, Khademi B, Bahmani Kashkouli M, Khataminia G, et al · · 2025 · cited 1× · PMID 40619554 · DOI 10.1007/s11046-025-00966-2
  3. Collaborative Study of COVID-19 Associated Rhino- Orbital-Cerebral Mucormycosis in Iran (CA-ROCM-IR): A Preliminary Report
    Eshraghi B, Khademi B, Mirmohammadkhani M, Khataminia G, et al · · 2023 · cited 1× · DOI 10.21203/rs.3.rs-2495890/v1

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Other recruiting trials for COVID-19

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