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NCT05095025
PENG: an Estimation of ED50 in Neck of Femur Fracture
NA trial testing Bupivacaine Hydrochloride 20ml injectate in Hip Fractures in 50 participants. Status unknown.
1 September 2022
Quick facts
| Lead sponsor | University College Cork |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | sequential |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 14 September 2021 |
| Primary completion | 1 September 2022 |
| Estimated completion | 1 October 2022 |
| Sites | 1 location across Ireland |
Drugs / interventions tested
- Bupivacaine Hydrochloride 20ml injectate — full drug profile →
Conditions studied
- Hip Fractures — all drugs for Hip Fractures →
- Pain, Acute — all drugs for Pain, Acute →
Sponsor
University College Cork
Who can join
18 and older, any sex, with Hip Fractures or Pain, Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The effective dose of local anaesthetic used in PENG blocks to achieve analgesia in patients with fractured neck of femur is unknown. It is planned to address this question using a dixon/massey sequential dosing methodology to establish the ED50 of 0.25% Bupivacaine.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05095025
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hip Fractures
Currently open trials in the same condition.
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- NCT06893406 — Cervical Myelopathy in Hip Fracture Patients · NA · recruiting
- NCT06565910 — Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG) · Phase 4 · recruiting
- NCT06455813 — What Laxative Should be Used After Hip Fracture Surgery? · Phase 4 · recruiting
Other University College Cork trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05095025 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University College Cork
- Last refreshed: 27 October 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05095025.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing