Last reviewed · How we verify
NCT05093686: RUBIES
RUBIES in Educational Settings
NA trial testing RUBIES in Autism Spectrum Disorder in 240 participants. Status unknown.
30 June 2024
Quick facts
| Lead sponsor | Seattle Children's Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 240 |
| Start date | 26 October 2021 |
| Primary completion | 30 June 2024 |
| Estimated completion | 31 July 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- RUBIES
- Usual Care Training
Conditions studied
- Autism Spectrum Disorder — all drugs for Autism Spectrum Disorder →
- Disruptive Behavior — all drugs for Disruptive Behavior →
Sponsor
Seattle Children's Hospital
Who can join
5 and older, any sex, with Autism Spectrum Disorder or Disruptive Behavior. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The proposed three-year pilot randomized trial aims to test the effectiveness of the newly-redesigned paraeducator-delivered RUBI for use in Educational Settings (RUBIES) intervention compared to usual care training in reducing disruptive behavior in 80 elementary-school children with ASD. Given the critical need to understand not just whether, but also how interventions work, this study also will examine paraeducator- and child-level mechanistic pathways of the RUBIES intervention.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Improving the Fit of Interventions for Autism in Schools: Lessons Learned Following Paraeducator Coaching on the RUBIES Program.
Tagavi DM, Puga S, Dick C, Dahiya AV, et al · · 2025 · cited 1× · PMID 41415622 · DOI 10.1080/10474412.2025.2578840
Verify or expand the search:
- PubMed search for NCT05093686
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of RUBIES
Trials testing the same drug.
- NCT07276750 — Coaching and Leadership in Autism Support Settings · NA · recruiting
- NCT04199533 — Iterative Redesign of a Behavioral Skills Training Program for Use in Educational Settings · completed
Other recruiting trials for Autism Spectrum Disorder
Currently open trials in the same condition.
- NCT07324057 — The Effects of Preoperative Intranasal Administration of Dexmedetomidine and Esketamine on Negative Postoperative Behavi · NA · recruiting
- NCT07493096 — Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disor · recruiting
- NCT07505290 — Efficacy of the Korean PEERS® for Preschoolers (PEERS®-PS-K) Social Skills Intervention: A Randomized Controlled Trial f · NA · active not recruiting
- NCT07524192 — A Self-Instructional Online Program for Early Childhood and Elementary Teachers Supporting Autistic Children and Childre · NA · recruiting
- NCT07432776 — Effect of an 8-Week Pickleball Program for Adults With Autism: A Feasibility Trial With a Delayed-Control Design · EARLY_PHASE1 · recruiting
Other Seattle Children's Hospital trials
Trials by the same sponsor.
- NCT07522112 — Evaluating a Shared Decision-making Intervention for Families About Firearm Storage · NA · not yet recruiting
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- NCT07424157 — Long-Term Follow-Up of Subjects Treated With Seattle Children's Therapeutics Gene Therapy Products · not yet recruiting
- NCT07148050 — Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimer · Phase 1 · recruiting
- NCT07097792 — Concussion Recovery and Support Program · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05093686 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Seattle Children's Hospital
- Last refreshed: 8 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05093686.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing