NCT05090592 is a clinical trial of orthokeratology in Myopia, sponsored by Buddhist Tzu Chi General Hospital.

Who is sponsoring NCT05090592?

NCT05090592 is sponsored by Buddhist Tzu Chi General Hospital.

What drugs are being tested in NCT05090592?

Interventions in NCT05090592: orthokeratology, 0.01 atropine.

Is NCT05090592 still recruiting?

NCT05090592 is currently status unknown. Last updated 25 October 2021.

Last reviewed 2021-10-25 · How we verify

NCT05090592

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Influence of Corneal Biomechanical Properties on Myopia Control

Status unknown Last updated 25 October 2021

What this trial tests

trial testing orthokeratology in Myopia in 100 participants. Status unknown.

Timeline

1 January 2021

Primary endpoint
30 July 2022

31 December 2022

Quick facts

Lead sponsor	Buddhist Tzu Chi General Hospital
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	100
Start date	1 January 2021
Primary completion	30 July 2022
Estimated completion	31 December 2022
Sites	1 location across Taiwan

Drugs / interventions tested

orthokeratology
0.01 atropine — full drug profile →

Conditions studied

Myopia — all drugs for Myopia →

Sponsor

Buddhist Tzu Chi General Hospital

Who can join

Adults 8 to 20, any sex, with Myopia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

to analyze the changes in corneal biomechanics of myopic children with different treatment (low concentration atropine eye drops and orthokeratology) and explore the possible mechanism of myopia control

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Assessment of Corneal Biomechanical Changes After Discontinuation of Long-Term Orthokeratology: A 2-Year Prospective Study.
Tsai HR, Wang JH, Chiu CJ. · · 2025 · PMID 40172526 · DOI 10.1167/tvst.14.4.5

Verify or expand the search:

Other trials of orthokeratology

Trials testing the same drug.

NCT05478356 — The Effects of Low-dose Atropine and Orthokeratology in Pediatric Myopia Control · NA · unknown
NCT07294404 — Peripheral Relative Refractive Power of Orthokeratology Lenses · completed
NCT05700240 — Effect of Orthokeratology on Myopia Progression in French Children · completed

Other recruiting trials for Myopia

Currently open trials in the same condition.

NCT07284966 — Comfort and Vision With TOTAL30 Multifocal Lenses · recruiting
NCT07078799 — Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery · NA · recruiting
NCT07585877 — Effect of Branched-Chain Amino Acid Supplementation on Myopia Progression · NA · active not recruiting
NCT07354945 — An Evaluation of Myopia Control Lenses on Wearing Experience in Myopic Children · NA · recruiting
NCT07229365 — Children's Viewing Behavior · NA · recruiting

Other Buddhist Tzu Chi General Hospital trials

Trials by the same sponsor.

NCT06141902 — The Effects of Jing Si Herbal Tea on Physical and Psychological Symptoms in Peripheral Blood Hematopoietic Stem Cell Don · NA · enrolling by invitation
NCT06818526 — Huandao Conditioning Application for Allergic Rhinitis Treatment · NA · not yet recruiting
NCT06744478 — Assessing the Magnitude of Anisometropia in Patients Wearing Misight 1 Day Contact Lens · enrolling by invitation
NCT07287657 — Exploring the Effects of Transcutaneous Electrical Acupoint Stimulation Therapy on Patients After Video-Assisted Thoraco · NA · enrolling by invitation
NCT07334938 — Effects of Far Infrared Rays and Transcutaneous Electrical Nerve Stimulation on Short Term Prognosis of Head and Neck Ca · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05090592 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Buddhist Tzu Chi General Hospital
Last refreshed: 25 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05090592.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing