Who is sponsoring NCT05090254?

NCT05090254 is sponsored by Universitätsklinikum Hamburg-Eppendorf.

What drugs are being tested in NCT05090254?

Interventions in NCT05090254: Treatment algorithms targeting cardiac output.

What condition does NCT05090254 study?

NCT05090254 studies Caridac Output-guided Goal-directed Hemodynamic Therapy, Oxygen Delivery, Oxygen Consumption, Microcirculatory Perfusion, Major Non-cardiac Surgery, Postoperative Acute Kidney Injury, Postoperative Acute Myocardial Injury.

Is NCT05090254 still recruiting?

NCT05090254 is currently completed. Last updated 30 June 2022.

Last reviewed 2022-06-30 · How we verify

NCT05090254: CUSTOM

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Perioperative Cardiac Output-guided GDT on Oxygen Delivery, Consumption, and Microcirculatory Perfusion

Completed NA Last updated 30 June 2022

What this trial tests

NA trial testing Treatment algorithms targeting cardiac output in Caridac Output-guided Goal-directed Hemodynamic Therapy in 78 participants. Completed in 31 May 2022.

Timeline

1 August 2021

Primary endpoint
31 May 2022

31 May 2022

Quick facts

Lead sponsor	Universitätsklinikum Hamburg-Eppendorf
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	78
Start date	1 August 2021
Primary completion	31 May 2022
Estimated completion	31 May 2022
Sites	1 location across Germany

Drugs / interventions tested

Treatment algorithms targeting cardiac output

Conditions studied

Caridac Output-guided Goal-directed Hemodynamic Therapy — all drugs for Caridac Output-guided Goal-directed Hemodynamic Therapy →
Oxygen Delivery — all drugs for Oxygen Delivery →
Oxygen Consumption — all drugs for Oxygen Consumption →
Microcirculatory Perfusion — all drugs for Microcirculatory Perfusion →

Sponsor

Universitätsklinikum Hamburg-Eppendorf — full company profile →

Who can join

18 and older, any sex, with Caridac Output-guided Goal-directed Hemodynamic Therapy or Oxygen Delivery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Perioperative cardiac output-guided goal-directed therapy (GDT) triggers fluid, vasopressor, and inotrope administration assuming that optimizing cardiac output (i.e., global blood flow) ensures adequate oxygen delivery and microcirculatory perfusion - that are usually not directly monitored during goal-directed therapy. There is increasing evidence that perioperative cardiac output-guided goal-directed therapy may reduce postoperative complications compared to routine hemodynamic management in high-risk patients having major surgery. The effect of cardiac output-guided goal-directed therapy algorithms on perioperative oxygen delivery and consumption as well as microcirculatory perfusion, however, is unknown. The investigators aim to investigate the effect of using different cardiac output-guided goal-directed therapy algorithms on perioperative oxygen delivery and consumption as well as sublingual microcirculatory perfusion compared to routine perioperative hemodynamic management in patients having major abdominal surgery with general anesthesia.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other Universitätsklinikum Hamburg-Eppendorf trials

Trials by the same sponsor.

NCT07443384 — Complications Associated With Radiofrequency Microneedling in Dermatology: a Delphi Consensus · not yet recruiting
NCT07385092 — Continuous Vital Sign Monitoring Versus Routine Spot-checks in Patients After Non-cardiac Surgery · NA · recruiting
NCT07009522 — Hamburg Emotion Awareness and Regulation Group Training for Autistic Adolescents (HEART) · EARLY_PHASE1 · not yet recruiting
NCT07115394 — EEG Measurements to Capture DBS-induced Electric Potentials · recruiting
NCT06955884 — Patient Experience of Transoral Versus Transnasal Awake Tracheal Intubation · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05090254 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universitätsklinikum Hamburg-Eppendorf
Last refreshed: 30 June 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05090254.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing