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NCT05089591

Intense Pulsed Light in Meibomian Gland Dysfunction

Status unknown NA Last updated 22 October 2021
What this trial tests

NA trial testing Intense Pulsed Light therapy in Meibomian Gland Dysfunction in 38 participants. Status unknown.

Timeline
20 October 2021
Primary endpoint
20 October 2022
1 November 2022

Quick facts

Lead sponsorPrim. Prof. Dr. Oliver Findl, MBA
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingdouble
Primary purposetreatment
Enrollment38
Start date20 October 2021
Primary completion20 October 2022
Estimated completion1 November 2022
Sites1 location across Austria

Drugs / interventions tested

Conditions studied

Sponsor

Prim. Prof. Dr. Oliver Findl, MBA

Who can join

18 and older, any sex, with Meibomian Gland Dysfunction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Meibomian gland dysfunction (MGD) is a major cause of dry eye disease (DED). Up to 86% of patients suffering from DED also show signs of MGD. Traditional treatment of MGD is based on eye lid hygiene and massage in combination with intensive usage of lubricants. Recently, a novel technology the intense pulsed light (IPL) therapy was introduced, which shows promising results in patients with meibomian gland dysfunction. Originating from field of dermatology, subjecting improvement of dry eye symptoms was recognized after the treatment of facial rosacea using IPL. Different hypotheses exist how IPL treatment might improve the situation in the dry eye patient. Warming of the eyelid, due to the light application and reduction of bacterial load are two possible mode of actions. Further, the used wavelengths in IPL may be modified that the light is only absorbed by oxygenated haemoglobin, which lead to an obliteration of telangiectasia and reduced inflammation on the lid margin. This principal is applied in the treatment of facial rosacea. Aim of this study is to investigate the effect of IPL therapy in patients with MGD on dry eye parameters as well as subjective complaints.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Safety and efficacy of a novel intense pulsed light system in patients with meibomian gland dysfunction: a randomized, double-masked, intra-individual controlled study.
    Schlatter A, Palkovits S, Amir-Asgari S, Ruiss M, et al · · 2025 · PMID 40524073 · DOI 10.1007/s10792-025-03622-2

Verify or expand the search:

Other recruiting trials for Meibomian Gland Dysfunction

Currently open trials in the same condition.

Other Prim. Prof. Dr. Oliver Findl, MBA trials

Trials by the same sponsor.

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Data sources for this page

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