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NCT05089591
Intense Pulsed Light in Meibomian Gland Dysfunction
NA trial testing Intense Pulsed Light therapy in Meibomian Gland Dysfunction in 38 participants. Status unknown.
20 October 2022
Quick facts
| Lead sponsor | Prim. Prof. Dr. Oliver Findl, MBA |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 38 |
| Start date | 20 October 2021 |
| Primary completion | 20 October 2022 |
| Estimated completion | 1 November 2022 |
| Sites | 1 location across Austria |
Drugs / interventions tested
- Intense Pulsed Light therapy
- Sham Treatment — full drug profile →
Conditions studied
- Meibomian Gland Dysfunction — all drugs for Meibomian Gland Dysfunction →
Sponsor
Prim. Prof. Dr. Oliver Findl, MBA
Who can join
18 and older, any sex, with Meibomian Gland Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Meibomian gland dysfunction (MGD) is a major cause of dry eye disease (DED). Up to 86% of patients suffering from DED also show signs of MGD. Traditional treatment of MGD is based on eye lid hygiene and massage in combination with intensive usage of lubricants. Recently, a novel technology the intense pulsed light (IPL) therapy was introduced, which shows promising results in patients with meibomian gland dysfunction. Originating from field of dermatology, subjecting improvement of dry eye symptoms was recognized after the treatment of facial rosacea using IPL. Different hypotheses exist how IPL treatment might improve the situation in the dry eye patient. Warming of the eyelid, due to the light application and reduction of bacterial load are two possible mode of actions. Further, the used wavelengths in IPL may be modified that the light is only absorbed by oxygenated haemoglobin, which lead to an obliteration of telangiectasia and reduced inflammation on the lid margin. This principal is applied in the treatment of facial rosacea. Aim of this study is to investigate the effect of IPL therapy in patients with MGD on dry eye parameters as well as subjective complaints.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Safety and efficacy of a novel intense pulsed light system in patients with meibomian gland dysfunction: a randomized, double-masked, intra-individual controlled study.
Schlatter A, Palkovits S, Amir-Asgari S, Ruiss M, et al · · 2025 · PMID 40524073 · DOI 10.1007/s10792-025-03622-2
Verify or expand the search:
- PubMed search for NCT05089591
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Meibomian Gland Dysfunction
Currently open trials in the same condition.
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- NCT06054217 — Effect of an Exploratory Vehicle on Meibomian Gland Dysfunction in Patients With Demodex · Phase 2 · active not recruiting
- NCT03652337 — Meibomian Gland Dysfunction Management · NA · active not recruiting
Other Prim. Prof. Dr. Oliver Findl, MBA trials
Trials by the same sponsor.
- NCT07425626 — Brillouin Scanning in Cataractous Eyes · active not recruiting
- NCT06624826 — Visual Performance of an Extended Depth of Focus IOL in an Emmetropic or Monovision Modality · NA · recruiting
- NCT06459284 — Instrument Tissue Interaction at the Grasp Site During Membrane Peeling of Epiretinal Membranes · completed
- NCT06948851 — New Postoperative Intraretinal Cystoid Changes After Vitrectomy With Membrane Peeling Due to Epiretinal Membranes · active not recruiting
- NCT07436247 — Pseudophakic Eyes With Presbyopia-correcting IOLs: OCT Biometry and Pyramid Aberrometry · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05089591 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Prim. Prof. Dr. Oliver Findl, MBA
- Last refreshed: 22 October 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05089591.
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