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NCT05088278
Long Term Clinical and Radiographical Outcomes of Different Anterior Cruciate Ligament Reconstruction Techniques
NA trial testing Anatomical single bundle ACL reconstruction with hamstrings in Anterior Cruciate Ligament Tear in 41 participants. Completed in 27 July 2023.
27 July 2023
Quick facts
| Lead sponsor | Istituto Ortopedico Rizzoli |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 41 |
| Start date | 1 April 2021 |
| Primary completion | 27 July 2023 |
| Estimated completion | 27 July 2023 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Anatomical single bundle ACL reconstruction with hamstrings
- Anatomical single bundle ACL reconstruction with patellar tendon
- ACL reconstruction with over the top plus lateral plasty technique
Conditions studied
- Anterior Cruciate Ligament Tear — all drugs for Anterior Cruciate Ligament Tear →
- Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →
Sponsor
Istituto Ortopedico Rizzoli — full company profile →
Who can join
Adults 30 to 70, any sex, with Anterior Cruciate Ligament Tear or Osteoarthritis, Knee. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate the long-term results of various anterior cruciate ligament reconstruction techniques. This assessment is necessary for the current context of anterior cruciate ligament research as several techniques and grafts are used in clinical practice, however, the various studies existing in the literature focus mainly only on the direct comparison of two techniques and usually with short-to-medium term follow-up. Since gonarthrosis is one of the most debated consequences of cruciate ligament reconstruction, a comparison of different long-term procedures would be desirable to have a clearer picture of the risks and benefits associated with different types of intervention.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A Comprehensive Framework to Evaluate the Effects of Anterior Cruciate Ligament Injury and Reconstruction on Graft and Cartilage Status through the Analysis of MRI T2 Relaxation Time and Knee Laxity: A Pilot Study.
Marchiori G, Cassiolas G, Berni M, Grassi A, et al · · 2021 · cited 7× · PMID 34947914 · DOI 10.3390/life11121383
Verify or expand the search:
- PubMed search for NCT05088278
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Anterior Cruciate Ligament Tear
Currently open trials in the same condition.
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- NCT06511232 — Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction · Phase 4 · recruiting
- NCT06524349 — Utilization of a 3D Printed Customized Knee Extender and At-Home Rehabilitation Program on Patient Outcomes Following AC · NA · active not recruiting
- NCT06353503 — Bone Marrow Aspirate Concentrate for Anterior Cruciate Ligament Tear Treatment. · NA · recruiting
Other Istituto Ortopedico Rizzoli trials
Trials by the same sponsor.
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- NCT07360964 — Clear Cell Chondrosarcoma in Italy · NA · active not recruiting
- NCT07140367 — "Transarterial Microembolization (TAME) in Inflammatory Knee Pathology" · recruiting
- NCT07102875 — Ready to Sail 2: A Pilot Study of Sail-Assisted Telerehabilitation in Rare Skeletal Diseases · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05088278 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istituto Ortopedico Rizzoli
- Last refreshed: 28 July 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05088278.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing