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NCT05088252
Desflurane and Anesthesia Recovery Period in Endonasal Endoscopic Pituitary Adenoma Resection
NA trial testing Desflurane in Pituitary Neoplasms in 112 participants. Completed in 31 May 2022.
10 May 2022
Quick facts
| Lead sponsor | Beijing Tiantan Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 112 |
| Start date | 1 December 2021 |
| Primary completion | 10 May 2022 |
| Estimated completion | 31 May 2022 |
| Sites | 1 location across China |
Drugs / interventions tested
- Desflurane (DESFLURANE) — full drug profile →
- Propofol (Propofol) — full drug profile →
Conditions studied
- Pituitary Neoplasms — all drugs for Pituitary Neoplasms →
Sponsor
Beijing Tiantan Hospital
Who can join
Adults 18 to 65, any sex, with Pituitary Neoplasms. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Nasal packing is required after endoscopic pituitary adenoma resection. The patient can only breathe through the mouth. The blood and secretion in the nasal cavity may be inhaled into the trachea after the operation. GH-secreting pituitary adenoma causes pharyngeal soft tissue and tongue hypertrophy. These conditions increase the risk of respiratory obstruction and hypoxemia during anesthesia recovery. Propofol total intravenous anesthesia has a rapid effect and a low incidence of nausea and vomiting. Patients anesthetized with desflurane recover quickly is conducive to early recovery of respiratory function and orientation. This study intends to compare the effects of desflurane and propofol on the quality of anesthesia recovery period in patients undergoing endonasal endoscopic pituitary adenoma resection and to provide clinical evidence for the use of desflurane in neurosurgical anesthesia.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05088252
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
Related trials
Other trials of Desflurane
Trials testing the same drug.
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- NCT07511634 — Comparison of Sevoflurane and Desflurane on ANI in Patients Undergoing General Anesthesia: a Prospective Randomized Cont · NA · not yet recruiting
- NCT07440758 — Low-Flow Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy · NA · not yet recruiting
- NCT07295158 — Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy · NA · recruiting
- NCT07123870 — Effect of Combined Intravenous-Inhalational Anesthesia (CIVIA) on Postoperative Recovery Patterns. · Phase 4 · recruiting
Other recruiting trials for Pituitary Neoplasms
Currently open trials in the same condition.
- NCT06282224 — Application of Augmented Reality Neuronavigation in Transnasal Endoscopic Skull Base Surgery · NA · recruiting
- NCT03665064 — Long Term Outcome Study in Patients With Pituitary Disorders · active not recruiting
Other Beijing Tiantan Hospital trials
Trials by the same sponsor.
- NCT07341854 — Dexamethasone Palmitate for Postoperative Pain · NA · not yet recruiting
- NCT07527013 — Stratified Blood Pressure Management Strategy After Endovascular Treatment for Acute Ischemic Stroke · Phase 3 · not yet recruiting
- NCT07520370 — Effect of Perioperative Ulinastatin on Postoperative Stroke in Patients With Brain Tumor · NA · not yet recruiting
- NCT07526987 — Efficacy and Safety of Minocycline in Patients With Acute Ischaemic Stroke Receiving Intravenous Thrombolysis · Phase 3 · not yet recruiting
- NCT07591207 — The Efficacy and Safety of Loxoprofen Sodium Patch in Relieving Postoperative Pain After Laparoscopic Surgery · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05088252 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Beijing Tiantan Hospital
- Last refreshed: 22 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05088252.
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