Last reviewed · How we verify
NCT05087680
An Acceptance Based PrEP Intervention to Engage Young Black MSM in the South
NA trial testing ACTPrEP in HIV Prevention in 66 participants. Currently enrolling.
1 December 2025
Quick facts
| Lead sponsor | Rhode Island Hospital |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 66 |
| Start date | 14 September 2023 |
| Primary completion | 1 December 2025 |
| Estimated completion | 1 December 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- ACTPrEP
- Enhanced Standard of Care
Conditions studied
- HIV Prevention — all drugs for HIV Prevention →
Sponsor
Rhode Island Hospital
Who can join
Adults 18 to 34, male only, with HIV Prevention. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Investigators will use a generalized framework for the adaptation of EBIs to inform the development of a brief Acceptance and Commitment Therapy (ACT)-based culturally appropriate pre-exposure prophylaxis (PrEP) intervention tailored to young Black men who have sex with men (YBMSM), named ACTPrEP.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Acceptance-Based Pre-Exposure Prophylaxis Intervention (ACTPrEP) to Engage Young Black Men Who Have Sex With Men in the Southern United States: Protocol for a Pilot Randomized Controlled Trial.
Arnold T, Giorlando KK, Barnett AP, Gaudiano BA, et al · · 2025 · PMID 40540736 · DOI 10.2196/65921
Verify or expand the search:
- PubMed search for NCT05087680
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Rhode Island Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05087680 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rhode Island Hospital
- Last refreshed: 19 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05087680.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing