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NCT05086679: COMFORTS II
Compression Stockings for Treating Vasovagal Syncope Trial
NA trial testing Compression Stockings with 25-30 mm Hg pressure in Syncope, Vasovagal in 268 participants. Status unknown.
10 October 2024
Quick facts
| Lead sponsor | Tehran Heart Center |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 268 |
| Start date | 14 March 2022 |
| Primary completion | 10 October 2024 |
| Estimated completion | 10 December 2024 |
| Sites | 1 location across Iran |
Drugs / interventions tested
- Compression Stockings with 25-30 mm Hg pressure
- Compression stockings with up to <=10 mm Hg pressure
- Lifestyle modification
Conditions studied
- Syncope, Vasovagal — all drugs for Syncope, Vasovagal →
Sponsor
Tehran Heart Center — full company profile →
Who can join
Adults 18 to 65, any sex, with Syncope, Vasovagal. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Syncope, a sudden, transient loss of consciousness (TLOC), is a common inconvenience of daily function and quality of life (QoL). The vasovagal syncope (VVS) is the most common type of syncope, which central and peripheral stimuli may trigger syncope by decreasing peripheral vascular resistance, bradycardia, or both. The venous return to the heart is one of these triggers which its reduction may occur due to prolonged standing, hot environment, hypovolemia, or redistribution of blood volume. The compression stockings may reduce syncopal episodes by increasing venous return. Although the use of compression stockings was never assessed in clinical trials, it could be a possible treatment for decreasing VVS recurrences.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05086679
- Europe PMC full search
- ASCO Meeting Library
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Related trials
Other recruiting trials for Syncope, Vasovagal
Currently open trials in the same condition.
- NCT06159764 — National Registry of Cardioneuroablation in Recurrent Reflex Syncope · recruiting
- NCT06496074 — Heart Rate Variation in Females Predicts Tilt Test Results · active not recruiting
- NCT06472102 — Cardioneuroablation: Fragmented Atrial Potentials, Intracardiac Echocardiography and Computed Tomography · NA · recruiting
- NCT06458140 — Cardioneuroablation and Ventricular Proarrhythmia · NA · recruiting
- NCT06440291 — Cardioneuroablation for Reflex Syncope and Exercise Capacity · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05086679 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tehran Heart Center
- Last refreshed: 15 April 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05086679.
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