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NCT05086536
Re-compensation and Its Clinical Characteristics in HBV Decompensated Cirrhosis
trial testing no intervention in Hepatitis B in 600 participants. Status unknown.
1 June 2022
Quick facts
| Lead sponsor | Beijing Friendship Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 600 |
| Start date | 15 October 2021 |
| Primary completion | 1 June 2022 |
| Estimated completion | 30 December 2022 |
| Sites | 7 locations across China |
Drugs / interventions tested
- no intervention
Conditions studied
- Hepatitis B — all drugs for Hepatitis B →
- Decompensated Cirrhosis — all drugs for Decompensated Cirrhosis →
Sponsor
Beijing Friendship Hospital
Who can join
Eligibility, any sex, with Hepatitis B or Decompensated Cirrhosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this study, treatment-naïve HBV-related cirrhosis patients were retrospectively enrolled at the first episode of decompensation (ascites or variceal hemorrhage). Patients were followed up every 6 months until death /liver transplantation or for 5 years. Clinical data from medical records about past history, first decompensated events, second /further decompensated events, HCC, and death/ liver transplantation were retrospectively collected. In this retrospective study, the incidence of re-compensation and its clinical characteristics were mainly explored.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Unstable Recompensation: An Intermediate Subtype in Patients With HBV-Related Decompensated Cirrhosis.
Xia S, He Z, Wu X, Hu Z, et al · · 2026 · cited 1× · PMID 41147778 · DOI 10.1111/apt.70430
Verify or expand the search:
- PubMed search for NCT05086536
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05086536 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Beijing Friendship Hospital
- Last refreshed: 21 October 2021
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