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NCT05084352: RAPID-TBI
Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury
trial in Traumatic Brain Injury in 1,200 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | University of Maryland, Baltimore |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 1,200 |
| Start date | 29 March 2021 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 October 2026 |
| Sites | 1 location across United States |
Conditions studied
- Traumatic Brain Injury — all drugs for Traumatic Brain Injury →
Sponsor
University of Maryland, Baltimore
Who can join
Adults 18 to 79, any sex, with Traumatic Brain Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction scores regarding neuroworsening and other outcomes following traumatic brain injury.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Rapid prediction of secondary neurologic decline after traumatic brain injury: a data analytic approach.
Podell J, Yang S, Miller S, Felix R, et al · · 2023 · cited 8× · PMID 36624110 · DOI 10.1038/s41598-022-26318-4
Verify or expand the search:
- PubMed search for NCT05084352
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Maryland, Baltimore trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05084352 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Maryland, Baltimore
- Last refreshed: 15 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05084352.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing