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NCT05083845
The Effect of Different Local Anesthetic Volumes on Postoperative Analgesia for Thoracotomy Patients With Erector Spinae Plane Block
NA trial testing Same blocks with different local anesthetic volume in Erector Spinae Plane Block in 60 participants. Completed in 9 July 2022.
9 June 2022
Quick facts
| Lead sponsor | Atatürk Chest Diseases and Chest Surgery Training and Research Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 25 August 2021 |
| Primary completion | 9 June 2022 |
| Estimated completion | 9 July 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Same blocks with different local anesthetic volume
Conditions studied
- Erector Spinae Plane Block — all drugs for Erector Spinae Plane Block →
- Local Anesthetic — all drugs for Local Anesthetic →
- Thoracotomy — all drugs for Thoracotomy →
- Postoperative Analgesia — all drugs for Postoperative Analgesia →
Sponsor
Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Who can join
Adults 18 to 65, any sex, with Erector Spinae Plane Block or Local Anesthetic. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
It is widely accepted that thoracotomy causes severe acute pain. This increases the frequency of postoperative pulmonary complications and postoperative morbidity. Many analgesic methods have been proposed for thoracotomy pain, including thoracic epidural analgesia (TEA), thoracic paravertebral block (TPVB), intercostal nerve blocks (ICSB), erector spinae plane block (ESPB), serratus anterior plane block (SAPB). Among these methods, ultrasound-guided TPVB and ESPB are the most used methods. TPVB has left its place to newer techniques such as ESPB due to its proximity to the pleura and its deeper location. ESPB is more superficial, easy to access, and less likely to have complications. In addition, ESPB application is increasing in patients who underwent thoracotomy and VATS. There is no consensus on the dose of analgesia in these studies. There are studies on volumes between 10 ml and 40 ml in the literature. In this study, it was aimed to compare the volumes of 20 ml and 30 ml containing local anesthetic at the same concentration (0.25% bupivacaine) of ESPB block to be performed with USG in patients who underwent thoracotomy.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparison of analgesic efficacy of different local anesthetic volumes for erector spinae plane block in thoracotomy patients; a prospective randomized trial.
Zengin M, Sazak H, Baldemir R, Ulger G, et al · · 2023 · cited 15× · PMID 36747119 · DOI 10.1186/s12871-023-02004-4
Verify or expand the search:
- PubMed search for NCT05083845
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Erector Spinae Plane Block
Currently open trials in the same condition.
- NCT07509957 — Effect of Preoperative Erector Spinae Plane Block on Recovery Quality, Time to Return to Daily Activities, and Postopera · NA · recruiting
- NCT07367568 — Costotransverse Foramen Block With Erector Spinae Plane Block in Modified Radical Mastectomy · NA · recruiting
- NCT07272577 — Erector Spinae Plane Block on Postoperative Analgesia in Patients Undergoing Laparoscopic Abdominal Surgeries · NA · recruiting
- NCT07251400 — Analgesic Efficacy of Erector Spinae and Rectus Sheath Block in Patients Undergoing Laparoscopic Inguinal Hernia Repair · NA · active not recruiting
- NCT07201285 — Edge of Laminar Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Video-Assisted Thoracoscopic Surg · NA · recruiting
Other Atatürk Chest Diseases and Chest Surgery Training and Research Hospital trials
Trials by the same sponsor.
- NCT07429669 — Comparative Analgesia and Respiratory Effects of Shoulder Blocks · NA · recruiting
- NCT06338007 — Relationship Between Hand Dynamometer Measurements, PFT, and mFI With Postoperative Outcomes · not yet recruiting
- NCT06341933 — Risk Factors for AKI in Patients Undergoing VATS for Pulmonary Resection · recruiting
- NCT06303557 — Effect of ESPB on Intraoperative Remifentanil Consumption · NA · completed
- NCT06247631 — STOP-Bang Questionnaire: A Predictor of Obstructive Sleep Apnea and Difficult Mask/Intubation? · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05083845 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
- Last refreshed: 12 July 2022
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