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NCT05083611: GraMI
Graded Motor Imagery in Phantom Limb Pain (GraMI Protocol)
NA trial testing GraMI in Phantom Limb Pain in 36 participants. Completed in 30 November 2023.
31 July 2023
Quick facts
| Lead sponsor | University of Vic - Central University of Catalonia |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 36 |
| Start date | 15 January 2023 |
| Primary completion | 31 July 2023 |
| Estimated completion | 30 November 2023 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- GraMI
Conditions studied
- Phantom Limb Pain — all drugs for Phantom Limb Pain →
Sponsor
University of Vic - Central University of Catalonia
Who can join
18 and older, any sex, with Phantom Limb Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The International Association for the Study of Pain defines phantom limb pain (PLP) as that pain referred to a part of the body that has been previously removed as if it were still present. It affects between 55-80% of the population who has suffered an amputation, but not in the same frequency and intensity. Graded motor imagery (GMI) is a progressive, physiotherapeutic treatment modality developed to train and reorganize the brain based on three consecutive techniques: laterality recognition, motor imagery, and mirror therapy. The scientific evidence on the implementation of GMI in PLP is scarce, noting that there is no standardized way to use it in this patient profile. Therefore, the need is generated to develop and validate a GMI protocol to address the PLP and test its effectiveness. The study hypothesis is that graded motor imagery is a conservative treatment method based on motor learning, neuroplasticity, and mirror neuron stimulation that may have positive effects in decreasing phantom limb pain in the amputated patient, and as a consequence, decrease the associated psychological factors and improve the quality of life and functionality of the person. A randomized clinical trial will be performed with simple blinding, following the CONSORT guide for this type of study. It will be carried out at the community level with supervision and follow-up by the principal investigator.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05083611
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Phantom Limb Pain
Currently open trials in the same condition.
- NCT07401966 — Amputations in Childhood and Neuropathic Pain · recruiting
- NCT06719245 — Prevention of PostAmputation Pain With Targeted Muscle Reinnervation · NA · recruiting
- NCT06702904 — Evaluation of Neuroprosthesis with Sensory Feedback for Modulation of Phantom Limb Pain and Enhancing Quality of Life · NA · recruiting
- NCT06813937 — Peripheral Magnetic Stimulation (PMS) Effects on Somatosensory Perception in Patients with Upper Limb Amputation · NA · recruiting
- NCT06644807 — Study of Phantom Limb Pain Suppression Using Neuromodulation Methods · NA · recruiting
Other University of Vic - Central University of Catalonia trials
Trials by the same sponsor.
- NCT07495254 — Effectiveness of Combined Super Inductive System (SIS) Therapy With Therapeutic Exercise and Health Education in Lateral · NA · not yet recruiting
- NCT07038031 — Nutrition in Action: Service-Learning Project · not yet recruiting
- NCT07017140 — Immersive Functional Virtual Reality in People With Acquired Brain Injury and Unilateral Spatial Neglect · NA · not yet recruiting
- NCT06583733 — Keep On Keep Up Bladder Health: Co-creating and Testing a Self-management Technological Solution for Ageing Well · NA · recruiting
- NCT06723587 — Chronic Effects of the Use of Instep Weights on Specific Capacities in Soccer Players · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05083611 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Vic - Central University of Catalonia
- Last refreshed: 31 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05083611.
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