Who is sponsoring NCT05079802?

NCT05079802 is sponsored by Ain Shams University.

What drugs are being tested in NCT05079802?

Interventions in NCT05079802: Double antibiotic paste mixed with chitosan nanoparticles, Double antibiotic paste mixed with propylene glycol.

What condition does NCT05079802 study?

NCT05079802 studies Resorption of Tooth or Root.

Is NCT05079802 still recruiting?

NCT05079802 is currently status unknown. Last updated 8 November 2021.

Last reviewed 2021-11-08 · How we verify

NCT05079802: LSTR

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical & Radiographic Evaluation of LSTR in Non-vital Primary Molars Using Two Different Vehicles

Status unknown Phase 3 Last updated 8 November 2021

What this trial tests

Phase 3 trial testing Double antibiotic paste mixed with chitosan nanoparticles in Resorption of Tooth or Root in 36 participants. Status unknown.

Timeline

1 December 2021

Primary endpoint
31 December 2023

31 March 2024

Quick facts

Lead sponsor	Ain Shams University
Phase	Phase 3
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	36
Start date	1 December 2021
Primary completion	31 December 2023
Estimated completion	31 March 2024

Drugs / interventions tested

Double antibiotic paste mixed with chitosan nanoparticles — full drug profile →
Double antibiotic paste mixed with propylene glycol — full drug profile →

Conditions studied

Resorption of Tooth or Root — all drugs for Resorption of Tooth or Root →

Sponsor

Ain Shams University

Who can join

Adults 4 to 7, any sex, with Resorption of Tooth or Root. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

LSTR will be done for primary teeth with significant root resorption needing non-vital pulp therapy to save such teeth for up to 12 months. The first part will be in vitro study to compare the antimicrobial effect of double antibiotic paste mixed with chitosan nanoparticle vs double antibiotic paste mixed with propylene glycol. The second part will be randomized clinical trial comparing the clinical and radiographic success of LSTR in study group where double antibiotic mix is mixed with chitosan nanoparticles and control group where double antibiotic paste is mixed with propylene glycol .

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Nanomaterials-Based Combinatorial Therapy as a Strategy to Combat Antibiotic Resistance.
León-Buitimea A, Garza-Cárdenas CR, Román-García MF, Ramírez-Díaz CA, et al · · 2022 · cited 23× · PMID 35740200 · DOI 10.3390/antibiotics11060794
Applications of Chitosan in Prevention and Treatment Strategies of Infectious Diseases.
Sinani G, Sessevmez M, Şenel S. · · 2024 · cited 16× · PMID 39339237 · DOI 10.3390/pharmaceutics16091201
Chitosan Micro/Nanocapsules in Action: Linking Design, Production, and Therapeutic Application.
Pérez-Pacheco Y, Tylkowski B, García-Valls R. · · 2025 · cited 12× · PMID 39860124 · DOI 10.3390/molecules30020252

Verify or expand the search:

Other Ain Shams University trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05079802 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 8 November 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05079802.

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