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NCT05075213

QuitBet Phase II: A Digital Social Game That Pays You to Stop Smoking

Completed NA Results posted Last updated 27 February 2026
What this trial tests

NA trial testing contingency management (deposit contract) in Smoking Cessation in 245 participants. Completed in 27 July 2024.

Timeline
1 November 2021
Primary endpoint
27 July 2024
27 July 2024

Quick facts

Lead sponsorWayBetter, Inc.
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment245
Start date1 November 2021
Primary completion27 July 2024
Estimated completion27 July 2024
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

WayBetter, Inc.

Who can join

21 and older, any sex, with Smoking Cessation. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Number of Participants Who Reported no Cigarette Smoking During the Past 7 Days Primary · 6 months after the start date of their first QuitBet game

At 6 month follow-up, participant reported no smoking during the past 7 days (survey question: "Have you smoked a cigarette, even just a puff, during the past 7 days?" with answer choices of "yes" or "no" - participant responded "no").

GroupValue95% CI
QuitBet30
QuitBet-NS (no Social Elements)35
Number of Participants Who Choose to Play a Second Game Secondary · 4 weeks after the start date of their first QuitBet game (end of game), when they were given the option to join a second game

Number of participants who chose to play a second QuitBet game

GroupValue95% CI
QuitBet19
QuitBet-NS (no Social Elements)34
Cigarettes Per Day During the Past 7 Days Secondary · 6 months after the start of their first QuitBet game

At 6 month follow up, the number of cigarettes the participant reported smoking during the previous 7 days (survey respondents only). In the 6 month follow-up survey, participants were first asked "Have you smoked a cigarette, even just a puff, during the past 7 days?" (yes/no answer choice). Participants who answered "no" were counted as smoking 0 cigarettes in this analysis. Participants who answered "yes" were then asked to report how many cigarettes they smoked on each day during the past week (day 1 being this day last week, day 2, day 3, day 4, day 5, day 6, day 7 being yesterday). The

GroupValue95% CI
QuitBet4.15± 6.63
QuitBet-NS (no Social Elements)3.25± 5.93
Number of Participants Who Used Smoking Cessation Medication Secondary · 6 month period beginning with the start of their first QuitBet game

Number of participants who reported use of any smoking cessation medication (including any form of nicotine replacement therapy, buproprion, or varencline) at any time during their participation in the study, from the start of their first QuitBet game until the last follow-up 6 months later

GroupValue95% CI
QuitBet35
QuitBet-NS (no Social Elements)44

Adverse events — posted to ClinicalTrials.gov

Time frame: From enrollment until the end of follow-up (6 months). Reporting threshold: 0%. Adverse-event reports describe events observed during the trial — not all are caused by the drug.

QuitBet
Serious: 0/109 (0%)
Deaths: 0/109
QuitBet-NS (no Social Elements)
Serious: 1/136 (1%)
Deaths: 0/136

Serious adverse events (1 terms)

ReactionSystemQuitBetQuitBet-NS (no Social Elem…
hospitalizationSurgical and medical procedures

Most-reported serious reactions: hospitalization.

Data from ClinicalTrials.gov NCT05075213 adverse events section.

Sponsor's own description

This study is a randomized controlled trial (RCT) of QuitBet, a digital contingency management program for smoking cessation. QuitBet combines social gaming elements with participant-funded financial incentives in the form of a deposit contract. QuitBet "players" deposit (called the "bet") a specified amount of their own money into the game's "pot." All "winners" who achieve the game's goal split the pot equally, such that their bet is fully refunded plus they receive extra money from the forfeited bets of players who did not meet the goal. Participants (N = 550) will be randomly assigned to QuitBet or QuitBet-NS (deposit contract only, no social elements). All participants will be offered a second game after their first game (up to 8 weeks total game duration) and will be asked to complete a survey after each game and at 1 and 4 months after the end of the second game (3 and 6 months after the start of their first game). The study will compare QuitBet vs. QuitBet-NS on smoking behavior outcomes and examine potential mediators of outcomes such as motivation, engagement, and satisfaction.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Smoking Cessation

Currently open trials in the same condition.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05075213.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing