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NCT05074056
Ketorolac on Postoperative Pain Reduction in Pediatric Patients with Adenotonsillectomy
Phase 4 trial testing Ketorolac in Adenotonsillar Hypertrophy in 142 participants. Completed in 30 December 2024.
30 December 2024
Quick facts
| Lead sponsor | St. Louis University |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 142 |
| Start date | 8 February 2022 |
| Primary completion | 30 December 2024 |
| Estimated completion | 30 December 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Ketorolac (KETOROLAC) — full drug profile →
Conditions studied
- Adenotonsillar Hypertrophy — all drugs for Adenotonsillar Hypertrophy →
- Obstructive Sleep Apnea — all drugs for Obstructive Sleep Apnea →
- Sleep-Disordered Breathing — all drugs for Sleep-Disordered Breathing →
- Acute Post Operative Pain — all drugs for Acute Post Operative Pain →
Sponsor
St. Louis University
Who can join
Adults 3 to 12, any sex, with Adenotonsillar Hypertrophy or Obstructive Sleep Apnea. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Postoperative pain management in the pediatric patient undergoing tonsillectomy is challenging. Despite being used in many procedures for postoperative pain management, perioperative ketorolac usage in pediatric tonsillectomy surgery is very limited. A recent survey showed that only 8.2% of anesthesiologists use NSAIDS for perioperative management of children with OSA undergoing adenotonsillectomy. The investigators propose to conduct a prospective, randomized study to investigate the opioid-sparing effect of perioperative ketorolac in pediatric patients who undergo tonsillectomies.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05074056
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Ketorolac
Trials testing the same drug.
- NCT07487246 — Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement · Phase 2 · not yet recruiting
- NCT07430085 — Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA · Phase 4 · not yet recruiting
- NCT06994442 — Optimizing Pain Treatment in Children On Mechanical Ventilation · Phase 3 · recruiting
- NCT06968806 — Study on Ketorolac for Improving Outcomes and Prognosis in Patients With Stanford Type A Aortic Dissection · Phase 3 · recruiting
- NCT06973785 — Non-Narcotic Pain Control After ACL Reconstruction · Phase 3 · recruiting
Other recruiting trials for Adenotonsillar Hypertrophy
Currently open trials in the same condition.
- NCT07045597 — Intranasal Midazolam for Preanasthetic Sedation for Preschool Children Undergoing Adenotonsillectomy. · NA · recruiting
- NCT06634264 — Comparison of Two Reeducation Methods in Children With Persistent Sleep Apnea, a Randomized Controlled Trial · NA · recruiting
Other St. Louis University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05074056 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by St. Louis University
- Last refreshed: 3 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05074056.
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