NCT05070416 is a NA clinical trial of Lithium disilicate crowns in Caries, sponsored by Ivoclar Vivadent AG.

Who is sponsoring NCT05070416?

NCT05070416 is sponsored by Ivoclar Vivadent AG.

What drugs are being tested in NCT05070416?

Interventions in NCT05070416: Lithium disilicate crowns.

What condition does NCT05070416 study?

NCT05070416 studies Caries, Dental Trauma.

Is NCT05070416 still recruiting?

NCT05070416 is currently terminated. Last updated 23 October 2025.

Are results published for NCT05070416?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2025-10-23 · How we verify

NCT05070416

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Lithium Disilicate Crowns Study

Terminated NA Results posted Last updated 23 October 2025

What this trial tests

NA trial testing Lithium disilicate crowns in Caries in 8 participants. Terminated before completion.

Timeline

4 October 2021

Primary endpoint
1 March 2023

1 March 2023

Quick facts

Lead sponsor	Ivoclar Vivadent AG
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	8
Start date	4 October 2021
Primary completion	1 March 2023
Estimated completion	1 March 2023
Sites	1 location across United States

Drugs / interventions tested

Lithium disilicate crowns

Conditions studied

Caries — all drugs for Caries →
Dental Trauma — all drugs for Dental Trauma →

Sponsor

Ivoclar Vivadent AG — full company profile →

Who can join

18 and older, any sex, with Caries or Dental Trauma. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Number of Crowns With Short-term Post-operative Sensitivity Primary · 4 weeks

assessed by patient's weekly feedback for 4 weeks after the treatment rating sensitivity from 1 "no sensitivity" to 4 "severe discomfort noted routinely with cold or pressure stimulation"

Group	Value	95% CI
Crowns self-adhesively cemented	0
Crowns adhesively luted	0

Quality Criteria (Modified FDI Criteria) Secondary · 4 weeks

assessed following the FDI criteria on a scale from 1 "very good" to 5 "unacceptable" (e.g. surface lustre, Staining, and colour match of restorations)

FDI 1 Surface Luster, FDI Score 1

Group	Value	95% CI
Crowns self-adhesively cemented	3
Crowns adhesively luted	5

FDI 1 Surface Luster, FDI Score 2-5

Group	Value	95% CI
Crowns self-adhesively cemented	0
Crowns adhesively luted	0

FDI 2 Surface Staining, FDI Score 1

Group	Value	95% CI
Crowns self-adhesively cemented	3
Crowns adhesively luted	5

FDI 2 Surface Staining, FDI Score 2-5

Group	Value	95% CI
Crowns self-adhesively cemented	0
Crowns adhesively luted	0

FDI 3 Colour, FDI Score 1

Group	Value	95% CI
Crowns self-adhesively cemented	2
Crowns adhesively luted	5

FDI 3 Colour, FDI Score 2

Group	Value	95% CI
Crowns self-adhesively cemented	1
Crowns adhesively luted	0

FDI 3 Colour, FDI Score 3-5

Group	Value	95% CI
Crowns self-adhesively cemented	0
Crowns adhesively luted	0

FDI 6 Marginal Adaption, FDI Score 1

Group	Value	95% CI
Crowns self-adhesively cemented	3
Crowns adhesively luted	5

Sponsor's own description

CAD-CAM crowns made of experimental lithium disilicate (shades A1, A2 and A3) are placed in patients by using either a dual-curing adhesive or a self-adhesive luting material in combination with total etch/universal bonding agent.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Caries

Currently open trials in the same condition.

NCT06677983 — Clinical Performance and Acceptance of Bioflx Crowns · NA · recruiting
NCT05748327 — Trial With Two New Tooth-colored Restorative Materials in Class I/II Cavities · NA · active not recruiting
NCT05505084 — Alveolar Ridge Preservation Following Tooth Extraction. · active not recruiting
NCT04796974 — Clinical Evaluation of "Cention Forte" Restorative Material · NA · active not recruiting

Other Ivoclar Vivadent AG trials

Trials by the same sponsor.

NCT06898411 — Clinical Evaluation on the Longevity of Glass Ceramic Based Single Tooth Restorations · not yet recruiting
NCT06238999 — Split-mouth Study of a New Flowable Composite in Non-carious Cervical Lesions · NA · active not recruiting
NCT06173167 — Clinical Evaluation of Full Contour Zirconia Chairside CAD/CAM Crowns · NA · recruiting
NCT06166849 — Clinical Evaluation of an Experimental Remineralization Product · NA · completed
NCT06131294 — Efficacy Evaluation of Two Different Fluoride Applications · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05070416 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ivoclar Vivadent AG
Last refreshed: 23 October 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05070416.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing