Impact of Timing of Midazolam Administration on Incidence of Postoperative Nausea and Vomiting

NCT05057767 NA COMPLETED

Postoperative nausea and vomiting (PONV), defined as nausea and/or vomiting occurring within 24 hours after surgery, affects between 20% and 30% of patients, As many as 70% to 80% of patients at high risk may be affected. The etiology of PONV is thought to be multifactorial, involving individual, anaesthetic and surgical risk factors. PONV results in increased patient discomfort and dissatisfaction and in increased costs related to length of hospital stay. Serious medical complications such as pulmonary aspiration, although uncommon, are also associated with vomiting. Patients with a higher risk of PONV often require a combination or multimodal approach of 2 or more interventions for effective risk reduction. Thus, researchers have explored additional nontraditional antiemetics, such as midazolam, that would aid in the multimodal prevention of PONV.

Details

Lead sponsor	Benha University
Phase	NA
Status	COMPLETED
Enrolment	120
Start date	Fri Sep 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Sun Jul 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Postoperative Nausea and Vomiting

Interventions

• Midazolam injection

Countries

Egypt