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NCT05056948
Artificial Intelligence Designed Single Tooth Dental Prostheses
trial testing artificial intelligence (AI) computer assisted design (CAD) in Dental Prosthesis in 250 participants. Completed in 30 May 2025.
1 September 2024
Quick facts
| Lead sponsor | The University of Hong Kong |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 250 |
| Start date | 1 September 2021 |
| Primary completion | 1 September 2024 |
| Estimated completion | 30 May 2025 |
| Sites | 1 location across Hong Kong |
Drugs / interventions tested
- artificial intelligence (AI) computer assisted design (CAD)
Conditions studied
- Dental Prosthesis — all drugs for Dental Prosthesis →
Sponsor
The University of Hong Kong
Who can join
18 and older, any sex, with Dental Prosthesis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Tooth loss is common and as consequence deteriorate patient's health and quality-of-life. Dental prostheses aim to restore patients' appearance and functions by replacement of missing teeth. The occlusal morphology and 3D position of the healthy natural teeth should be adopted by the dental prostheses (biomimetic). Despite computer-assisted design (CAD) software are available for designing dental prostheses, considerable clinical time are still required to fit the dental prostheses into patients' occlusion (teeth-to-teeth relationship). Teeth of an individual subjects are genetically controlled and exposed to mostly identical oral environment, therefore the occlusal morphology and 3D position of teeth are inter-related. It is hypothesized that artificial intelligence (AI) can automated designing the single-tooth dental prostheses from the features of remaining dentition.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Artificial intelligence-designed single molar dental prostheses: A protocol of prospective experimental study.
Chau RCW, Chong M, Thu KM, Chu NSP, et al · · 2022 · cited 20× · PMID 35653388 · DOI 10.1371/journal.pone.0268535
Verify or expand the search:
- PubMed search for NCT05056948
- Europe PMC full search
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05056948 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The University of Hong Kong
- Last refreshed: 3 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05056948.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing