Who is sponsoring NCT05054309?

NCT05054309 is sponsored by Société des Produits Nestlé (SPN).

What drugs are being tested in NCT05054309?

Interventions in NCT05054309: Bifidobacterium longum.

What condition does NCT05054309 study?

NCT05054309 studies IBS - Irritable Bowel Syndrome.

Is NCT05054309 still recruiting?

NCT05054309 is currently completed. Last updated 28 February 2025.

Last reviewed 2025-02-28 · How we verify

NCT05054309: Mood-01

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Trial to Evaluate the Effects of Bifidobacterium Longum NCC3001 on Intestinal and Psychological Symptoms in Subjects With Irritable Bowel Syndrome

Completed NA Last updated 28 February 2025

What this trial tests

NA trial testing Bifidobacterium longum in IBS - Irritable Bowel Syndrome in 146 participants. Completed in 14 February 2025.

Timeline

11 February 2022

Primary endpoint
4 December 2024

14 February 2025

Quick facts

Lead sponsor	Société des Produits Nestlé (SPN)
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	other
Enrollment	146
Start date	11 February 2022
Primary completion	4 December 2024
Estimated completion	14 February 2025
Sites	11 locations across Canada

Drugs / interventions tested

Bifidobacterium longum

Conditions studied

IBS - Irritable Bowel Syndrome — all drugs for IBS - Irritable Bowel Syndrome →

Sponsor

Société des Produits Nestlé (SPN) — full company profile →

Who can join

Adults 18 to 70, any sex, with IBS - Irritable Bowel Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a prospective, randomized, placebo-controlled, double-blind, multi-center parallel- design study to evaluate the effect of BL NCC3001 in subjects with Irritable Bowel Syndrome.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Gut Microbiome-Brain Alliance: A Landscape View into Mental and Gastrointestinal Health and Disorders.
Sasso JM, Ammar RM, Tenchov R, Lemmel S, et al · · 2023 · cited 100× · PMID 37156006 · DOI 10.1021/acschemneuro.3c00127
Metabolome-associated psychological comorbidities improvement in irritable bowel syndrome patients receiving a probiotic.
Martin FP, Cominetti O, Berger B, Combremont S, et al · · 2024 · cited 20× · PMID 38717445 · DOI 10.1080/19490976.2024.2347715

Verify or expand the search:

Other trials of Bifidobacterium longum

Trials testing the same drug.

NCT07420231 — Evaluation of the Synergistic Effect of Combining a Prebiotic and a Postbiotic on Intestinal Discomfort · NA · not yet recruiting
NCT06639516 — Therapeutic Effect of Bifidobacterium Longum in Patients with Acute Pancreatitis: a Randomized, Double-Blind, Placebo-Co · NA · not yet recruiting
NCT04911556 — the Effect of Probiotics on Aging Population · NA · unknown
NCT04042181 — The Effects of Supplementation of a Probiotic, B. Longum, on BMI and Anthropometric Outcomes in Overweight/Obese Adults. · NA · unknown
NCT03056846 — Probiotics on Stress-associated Gastrointestinal Function in University Students · NA · completed

Other recruiting trials for IBS - Irritable Bowel Syndrome

Currently open trials in the same condition.

NCT06993272 — Relaxation Music for Chronic Pain · NA · active not recruiting
NCT06684470 — Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a Neuromodul · EARLY_PHASE1 · recruiting
NCT06117865 — Digital Treatment of Irritable Bowel Syndrome (IBS) · NA · active not recruiting
NCT06215222 — Capsule Microbiota Sampling in IBS/Functional Gastrointestinal Disease · recruiting
NCT05815602 — Ebastine Versus Mebeverine in IBS Patients · Phase 3 · recruiting

Other Société des Produits Nestlé (SPN) trials

Trials by the same sponsor.

NCT07312201 — Oral Nutritional Supplementation in Children With Growth Concerns · NA · not yet recruiting
NCT07378111 — Vegetarian Tube Feed Study · NA · not yet recruiting
NCT07439718 — The Effects of an Oral Nutritional Intervention on the Small Intestine Microbiome · NA · recruiting
NCT07341464 — Acceptability and Tolerance Study of Bolus Tube Feed With Food Blends · NA · recruiting
NCT07127198 — Tolerance and Appetite Reduction of a Nutritional Solution With Intragastric Gelation Properties · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05054309 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Société des Produits Nestlé (SPN)
Last refreshed: 28 February 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05054309.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing