Who is sponsoring NCT05052541?

NCT05052541 is sponsored by University of Colorado, Denver.

What condition does NCT05052541 study?

NCT05052541 studies Back Pain, Neck Pain.

What drugs are being tested in NCT05052541?

Interventions: THC/CBD, THC, Placebo.

What is the status of NCT05052541?

NCT05052541 is currently RECRUITING.

Last reviewed 2026-01-21 · How we verify

Safety and Efficacy of Oral Cannabis in Chronic Spine Pain

NCT05052541 Phase 3 RECRUITING

The overall objectives of this study are to investigate the efficacy of extended cannabis treatment to reduce patient exposure to prescription opioids through its use 1) as a non-opioid analgesic treatment, and 2) as a therapy for reducing high-dose opioid use in patients with chronic spine pain.

Details

Lead sponsor	University of Colorado, Denver
Phase	Phase 3
Status	RECRUITING
Enrolment	157
Start date	2026-01
Completion	2027-06

Conditions

Back Pain
Neck Pain

Interventions

THC/CBD
THC
Placebo

Primary outcomes

Change in chronic pain as measured by the Visual Analog Scale (VAS) for pain — Weekly, up to week 22
The Visual Analog Scale (VAS) for pain is a 0-100mm visual scale anchored by "no pain" and "worst possible pain".
Change in opioid dose as measured in morphine milligram equivalents (MME) — Weekly, up to week 22

Countries

United States