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NCT05048524
Peri-operative SLOG for Localized Pancreatic Cancer
Phase 2 trial testing S-1, leucovorin, oxaliplatin and gemcitabine in Pancreatic Ductal Adenocarcinoma in 64 participants. Status unknown.
24 August 2024
Quick facts
| Lead sponsor | National Health Research Institutes, Taiwan |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 64 |
| Start date | 3 September 2021 |
| Primary completion | 24 August 2024 |
| Estimated completion | 24 August 2025 |
| Sites | 3 locations across Taiwan |
Drugs / interventions tested
- S-1, leucovorin, oxaliplatin and gemcitabine — full drug profile →
Conditions studied
- Pancreatic Ductal Adenocarcinoma — all drugs for Pancreatic Ductal Adenocarcinoma →
- Pancreas Cancer — all drugs for Pancreas Cancer →
Sponsor
National Health Research Institutes, Taiwan
Who can join
20 and older, any sex, with Pancreatic Ductal Adenocarcinoma or Pancreas Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
1. To evaluate the efficacy of neoadjuvant chemotherapy SLOG in localized pancreatic cancer 2. To evaluate the safety profile in patients with pancreatic cancer who receive neoadjuvant SLOG 3. To collect tumor tissue and peripheral blood samples from the patients for a comprehensive biomarker evaluation
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
The experience of neoadjuvant chemotherapy versus upfront surgery in resectable pancreatic cancer: a cross sectional study.
Su YY, Chao YJ, Wang CJ, Liao TK, et al · · 2023 · cited 12× · PMID 37300888 · DOI 10.1097/js9.0000000000000495 -
Improved survival with induction chemotherapy and conversion surgery in locally advanced unresectable pancreatic cancer: a single institution experience.
Su YY, Ting YL, Wang CJ, Chao YJ, et al · · 2022 · cited 9× · PMID 35693078 -
Current status and perspectives of genetic testing in gastrointestinal cancer (Review).
Matsuoka T, Yashiro M. · · 2024 · cited 4× · PMID 38058469 · DOI 10.3892/ol.2023.14155 -
Single-cell RNA sequencing: enhancing the predictive accuracy of tumor immunotherapy efficacy.
Zhou W, Huang Z, Wu Z, Tang M, et al · · 2025 · cited 3× · PMID 40857744 · DOI 10.1042/ebc20253017
Verify or expand the search:
- PubMed search for NCT05048524
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Pancreatic Ductal Adenocarcinoma
Currently open trials in the same condition.
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- NCT07261631 — Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors · Phase 1 · recruiting
Other National Health Research Institutes, Taiwan trials
Trials by the same sponsor.
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- NCT07138261 — Taiwanese Anaplastic Thyroid Cancer Registry · not yet recruiting
- NCT07151365 — Plant-based Diets and Healthy Aging · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05048524 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Health Research Institutes, Taiwan
- Last refreshed: 27 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05048524.
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