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NCT05046340: AFRIC
Applicability of Fluid Responsiveness Indices in Circulatory Failure (AFRIC Study) Study Project
trial testing Passive leg raising in Shock in 200 participants. Status unknown.
28 February 2023
Quick facts
| Lead sponsor | Bicetre Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 200 |
| Start date | 10 January 2019 |
| Primary completion | 28 February 2023 |
| Estimated completion | 31 December 2023 |
| Sites | 1 location across France |
Drugs / interventions tested
- Passive leg raising
Conditions studied
- Shock — all drugs for Shock →
- Acute Circulatory Failure — all drugs for Acute Circulatory Failure →
Sponsor
Bicetre Hospital
Who can join
18 and older, any sex, with Shock or Acute Circulatory Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Fluid administration is one of the main strategies for patients with acute circulatory failure. However, about half of the patients could not benefit from the fluid administration after the ICU admission. Thus predict the effect of fluid responsiveness is essential. There are sevral indices or tests can be used, such as pulse pressure variation (PPV), end-expiratory occulsion test (EEOT), passive leg raising (PLR), etc. Question of the prevalence of cases in which the different predictive indices of fluid responsiveness in intensive care unit (ICU) are not applicable.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05046340
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Passive leg raising
Trials testing the same drug.
- NCT04574011 — Fluid Responsiveness in Spontaneously Ventilating Patient · NA · unknown
- NCT03788707 — Capnogram and Fluid Responsiveness · NA · withdrawn
- NCT05797584 — Right Ventricular Contractile Reserve in HF · NA · unknown
Other recruiting trials for Shock
Currently open trials in the same condition.
- NCT07273643 — Characterization of Extracellular Vesicles From the Cord Blood of Extremely Preterm New Borns and Their Correlation With · recruiting
- NCT07009665 — Fluid Management and Individualized Resuscitation in Sepsis · NA · recruiting
- NCT06713668 — Augmented Pacing for Shock in the Cardiac Intensive Care Unit · NA · recruiting
- NCT06930235 — Effectiveness of Midodrine as an Adjuvant to Norepinephrine in Weaning Critically Ill Patients From Vasopressors · NA · recruiting
- NCT06920173 — Pulse Study: Peripheral Use of Low-dose Vasopressors for Safety and Efficacy in the Intensive Care Unit · Phase 2 · recruiting
Other Bicetre Hospital trials
Trials by the same sponsor.
- NCT07453901 — The Multicentre Prospective Observational Study on the Management of Septic Shock · not yet recruiting
- NCT06772038 — Fluid Responsiveness and Venous Congestion Evolution During Volume Expansion · recruiting
- NCT06839404 — Pharmacodynamic Analysis of the HaemOdynamic Effects of a Standard Fluid BolUS · recruiting
- NCT05676723 — Thoracic Fluid Content by Bioimpedance-based Starling System · completed
- NCT04870892 — Effects of Norepinephrine and Volume Expansion in Capillary Refill Time in Septic Shock · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05046340 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Bicetre Hospital
- Last refreshed: 14 February 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05046340.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing