Who is sponsoring NCT05040945?

NCT05040945 is sponsored by Damascus University.

What drugs are being tested in NCT05040945?

Interventions in NCT05040945: Traditional corticotomy, Flapless corticotomy.

What condition does NCT05040945 study?

NCT05040945 studies Class II Division 1 Malocclusion.

Is NCT05040945 still recruiting?

NCT05040945 is currently completed. Last updated 10 September 2021.

Last reviewed 2021-09-10 · How we verify

NCT05040945

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the Levels of Pain and Discomfort Associated With Two Techniques of Corticotomy

Completed NA Last updated 10 September 2021

What this trial tests

NA trial testing Traditional corticotomy in Class II Division 1 Malocclusion in 34 participants. Completed in 15 May 2019.

Timeline

15 February 2018

Primary endpoint
31 July 2018

15 May 2019

Quick facts

Lead sponsor	Damascus University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	34
Start date	15 February 2018
Primary completion	31 July 2018
Estimated completion	15 May 2019
Sites	1 location across Syria

Drugs / interventions tested

Traditional corticotomy
Flapless corticotomy

Conditions studied

Class II Division 1 Malocclusion — all drugs for Class II Division 1 Malocclusion →

Sponsor

Damascus University

Who can join

Adults 18 to 30, any sex, with Class II Division 1 Malocclusion. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to estimate the levels of pain and discomfort associated with the en-masse retraction of the six upper anterior teeth and assisted by either conventional or flapless corticotomy. Thirty-four adult patients exhibiting class П division 1 malocclusion will be randomly allocated to either the conventional corticotomy group or the flapless corticotomy group, and they will be treated by extraction of maxillary first premolars with applying mini-screws between maxillary second premolar and first molar as temporary skeletal anchorage devices (TSADs). The levels of pain and discomfort will be rated after 24 hours of corticotomy (T1), four days (T2), seven days (T3), 14 days (T4) and after 28 days of corticotomy, by asking the patients to fill in a questionnaire for assessing levels of pain and discomfort.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Traditional corticotomy

Trials testing the same drug.

NCT05928143 — Patient Outcomes Associated With Two Accelerated Method of Retraction of Upper Front Teeth · NA · completed
NCT04847492 — Evaluation of Upper Anterior Teeth Retraction Rate Assisted by Two Corticotomy Techniques · NA · completed
NCT03279042 — Effectiveness of Two Corticotomy Techniques in Retracting the Upper Anterior Teeth by Using Miniscrews · NA · completed

Other Damascus University trials

Trials by the same sponsor.

NCT07532161 — Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery · NA · not yet recruiting
NCT07515612 — The Impact of Valerian and Chamomile on Children's Anxiety in the Dental Clinic. · NA · recruiting
NCT07272798 — Cardiac Self-Efficacy in Patients With Chronic Thromboembolic Pulmonary Hypertension · recruiting
NCT07426523 — Effectiveness of Needle-Free Infiltration Anesthesia in Reduction of Dental Pain and Anxiety During Local Anesthesia. · NA · completed
NCT07366788 — Clinical Outcomes of Mandibular Primary Molar Extraction Using Physics Forceps in Children · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05040945 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Damascus University
Last refreshed: 10 September 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05040945.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing