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A Study on the Brain Mechanism of cTBS in Improving Medication-resistant Auditory Hallucinations in Schizophrenia
This study is dedicated to exploring the brain mechanism of medication-resistant auditory hallucinations and developing effective treatment methods for them by using both cross-sectional and longitudinal designs. The continuous theta burst stimulation(cTBS) treatment mode, with the left cerebellum Crus II as the stimulation target, is applied to treat the schizophrenia patients with the medication-resistant auditory hallucinations. At the same time, the first-episode schizophrenia patients with auditory hallucinations were recruited as a test cohort to examine that brain mechanism of general auditory hallucinations in schizophrenia may be the structural and functional abnormalities in the temporoparietal circuit.
Details
| Lead sponsor | Central South University |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 200 |
| Start date | Thu Sep 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Thu Nov 30 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Schizophrenia
Interventions
- Antipsychotic drugs
- cTBS（the left temporoparietal cortex as the stimulation target）
- cTBS （the left cerebellum Crus II as the stimulation target）
Countries
China