Last reviewed · How we verify
NCT05037370
CONTOURA vs WFO Ablation PRK & LASIK
NA trial testing Wave-Front Optimized (WFO) ablation vs Topography-guided (TG) ablation in Refractive Surgery in 400 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | 59th Medical Wing |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 400 |
| Start date | 22 April 2021 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Wave-Front Optimized (WFO) ablation vs Topography-guided (TG) ablation
Conditions studied
- Refractive Surgery — all drugs for Refractive Surgery →
Sponsor
59th Medical Wing — full company profile →
Who can join
Adults 21 to 50, any sex, with Refractive Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a prospective randomized contralateral double-masked study. Each patient will be randomized as to which eye undergoes wave-front optimized (WFO) vs. wave-front guided (WFG) during Photorefractive keratectomy (PRK) or Laser-assisted in situ Keratomileusis (LASIK) surgery to determine which ablation profile provides the best visual outcome.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05037370
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Refractive Surgery
Currently open trials in the same condition.
- NCT07481487 — Outcomes of Cataract & Refractive Procedures · recruiting
- NCT07146828 — Clinical Application Research of 5-Degree (0.05 D) Precision Optometry in Corneal Refractive Surgery · NA · recruiting
- NCT06982807 — Clinical Study of SMILE 4.0-VISULYZE in Correcting Refractive Errors · NA · recruiting
- NCT06448468 — Analysis of Ocular Surface Microbiota in Dry Eye Patients After Femtosecond Laser-assisted In-situ Keratomileusis (FS-LA · recruiting
- NCT06264804 — Risk Factors for Progressive Suction Loss in Corneal Refractive Surgery · recruiting
Other 59th Medical Wing trials
Trials by the same sponsor.
- NCT06892340 — Evaluation of a Device to Reduce Motion Sickness and Spatial Disorientation · NA · recruiting
- NCT07126756 — LASIK iDesign vs SMILE · NA · active not recruiting
- NCT07128316 — LASIK Using Contoura With Phorcides vs. iDesign · NA · active not recruiting
- NCT05844397 — SMILE vs. LASIK Using Contoura With Phorcides · NA · completed
- NCT05844384 — Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05037370 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by 59th Medical Wing
- Last refreshed: 14 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05037370.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing