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NCT05033249
The Utility of Immature Granulocyte Count on the Prediction of Acute Appendicitis in the Suspected Acute Appendicitis
trial testing Immature granulocyte count in Acute Appendicitis in 186 participants. Completed in 1 July 2019.
1 July 2019
Quick facts
| Lead sponsor | Kahramanmaras Sutcu Imam University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 186 |
| Start date | 1 January 2019 |
| Primary completion | 1 July 2019 |
| Estimated completion | 1 July 2019 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Immature granulocyte count
- Immature granulocyte percentage
Conditions studied
- Acute Appendicitis — all drugs for Acute Appendicitis →
Sponsor
Kahramanmaras Sutcu Imam University
Who can join
18 and older, any sex, with Acute Appendicitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Acute appendicitis is the most common cause of abdominal pain requiring surgery in the emergency department. The whole life acute appendicitis rate is 7%. Only half of the patients with acute appendicitis are presented with typical periumbilical pain following by nausea, vomiting, and the migration of pain to the right lower quadrant. The diagnosis of acute appendicitis is based on the patient's medical history, physical examination, and laboratory findings. The Alvarado scoring system (ASS), recommends discharge, observation, and surgical intervention to patients. However, such scoring systems should not be used as the only method in diagnosis. Increased imaging use in patients with suspected acute appendicitis improved the rate of correct diagnosis. American College of Radiology Appropriateness Criteria (ACR) recommends computerized tomography (CT) as the primary imaging method to confirm the diagnosis of acute appendicitis in adults. However, CT imaging has some disadvantages, such as radiation exposure, undesirable effects associated with the use of contrast agents, and increased workload in the emergency room. The count of immature granulocytes (IGC), which is an indicator of increased activation of the bone marrow, and the percentage of IG (IGP), which is the ratio of IGs to the total white blood cell count, are also has been used differentiation of complicated acute appendicitis from uncomplicated acute appendicitis, and other inflammatory pathologies. Nowadays automatic blood analyzers can easily measure the amount and percentage of IGs simultaneously in a complete blood count test with advances in technology. It is aimed to investigate the utility of IGC and IGP on the prediction of suspected acute appendicitis according to the ASS and its effect on the need for CT scanning.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05033249
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Related trials
Other recruiting trials for Acute Appendicitis
Currently open trials in the same condition.
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- NCT07492329 — Antibiotics vs Surgery in Acute Appendicitis · NA · active not recruiting
- NCT06563349 — Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy · Phase 4 · recruiting
- NCT03236961 — Optimizing the Antibiotic Treatment of Uncomplicated Acute Appendicitis · NA · active not recruiting
Other Kahramanmaras Sutcu Imam University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05033249 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kahramanmaras Sutcu Imam University
- Last refreshed: 23 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05033249.
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