40 and older, any sex, with Sedentary Lifestyle. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Percent Change in StepsPrimary· Percent Change of Steps from baseline to Weeks 3, 4, 5, 6, 7, and 8
Steps were automatically synced from the Fitbit for both conditions daily. Days with 500 or fewer recorded steps were coded as missing. Weekly step averages were calculated for weeks with 4 or more days not coded missing. The first two weeks of baseline steps were averaged to form the baseline step.
Percent change of steps was calculated as the difference between the average weekly steps during the intervention (weeks 3-8) and baseline steps divided by baseline steps.
Percent Change From Baseline to Week 3
Group
Value
95% CI
Social Exergame Treatment Group
4.68
± 29
Control Group
4.77
± 23
Percent Change From Baseline to Week 4
Group
Value
95% CI
Social Exergame Treatment Group
11.87
± 33
Control Group
2.69
± 22
Percent Change From Baseline to Week 5
Group
Value
95% CI
Social Exergame Treatment Group
10
± 46
Control Group
11.11
± 26
Percent Change From Baseline to Week 6
Group
Value
95% CI
Social Exergame Treatment Group
5.33
± 38
Control Group
11.26
± 28
Percent Change From Baseline to Week 7
Group
Value
95% CI
Social Exergame Treatment Group
3.11
± 35
Control Group
5.66
± 33
Percent Change From Baseline to Week 8
Group
Value
95% CI
Social Exergame Treatment Group
10
± 48
Control Group
-6.45
± 24
Lubben Social Network Scale (LSNS)Primary· Pretest (before week 1) and posttest (after week 8)
Self-report measure of social support from the Lubben Social Network Scale for family and friends with scores summed across 18 items. Possible scores range from 0-60, with higher scores indicating higher social support.
Pretest
Group
Value
95% CI
Social Exergame Treatment Group
32.32
± 7.98
Control Group
30.64
± 9.26
Posttest
Group
Value
95% CI
Social Exergame Treatment Group
32.23
± 9.81
Control Group
28.40
± 9.15
Social Connectedness ScalePrimary· Baseline (Average of Week 1 and 2), Weekly during the intervention from Week 3 to 8
Social Connectedness Scale was administered weekly during the intervention with the following subscales:
relationship salience, shared understandings, knowing other's experiences, satisfaction with the contact quantity and quality, and dissatisfaction with contact quantity. Scores were averaged across items from each subscale and possible scores ranged from 1 to 7 with higher scores indicating a higher level of the subscale.
Knowing Others' Experience Baseline (Average of Week 1 and 2)
Group
Value
95% CI
Social Exergame Treatment Group
4.88
± .92
Control Group
4.72
± 1.06
Knowing Others' Experience Week 3
Group
Value
95% CI
Social Exergame Treatment Group
4.7
± 1.22
Control Group
4.72
± 1.18
Knowing Others' Experience Week 4
Group
Value
95% CI
Social Exergame Treatment Group
4.96
± 1.23
Control Group
4.87
± 1.12
Knowing Others' Experience Week 5
Group
Value
95% CI
Social Exergame Treatment Group
4.85
± 1.4
Control Group
4.67
± 1.17
Knowing Others' Experience Week 6
Group
Value
95% CI
Social Exergame Treatment Group
5
± 1.14
Control Group
4.67
± 1.28
Knowing Others' Experience Week 7
Group
Value
95% CI
Social Exergame Treatment Group
4.63
± 1.22
Control Group
4.66
± 1.27
Knowing Others' Experience Week 8
Group
Value
95% CI
Social Exergame Treatment Group
4.77
± 1.31
Control Group
4.70
± 1.33
Relationship Salience Baseline (Average of Week 1 and 2)
The UCLA Loneliness Scale captures one's subjective feelings of loneliness over the past week for weekly surveys and over the past month for pretest and posttest surveys (20 items with ratings from 1 "Never" to 4 "Often"). The scores were averaged across the 20 items, with a score ranging from 1-4. A higher score indicates more loneliness.
Pretest
Group
Value
95% CI
Social Exergame Treatment Group
2.21
± 0.63
Control Group
2.21
± 0.73
Posttest
Group
Value
95% CI
Social Exergame Treatment Group
2.08
± 0.75
Control Group
2.24
± 0.76
Positive and Negative Affect Schedule (PANAS) (20 Items)Primary· Pretest (before week 1) and posttest (after week 8)
Positive and Negative Affect Schedule (PANAS) (20 items) asks participants to report how often participants felt positive and negative feelings over the past week for weekly surveys, and over the past month for pre-test and post-test surveys. Scores were averaged across the items (Total positive and negative affect scores can range from 0-4, with a higher score indicating a higher level of positive affect or negative affect).
Perceived Stress Scale (PSS) asks participants' stress perception over the last month and scores were summed across the items (Possible scores range from 0 to 40 with higher scores indicating higher stress).
Pretest
Group
Value
95% CI
Social Exergame Treatment Group
23.08
± 7.92
Control Group
22.82
± 8.66
Posttest
Group
Value
95% CI
Social Exergame Treatment Group
22.32
± 8.44
Control Group
22.20
± 7.78
Brief Symptom Inventory (BSI)Primary· Baseline (Average of Week 1 and 2), Weekly during the intervention from Week 3 to 8
Brief Symptom Inventory (BSI) captures participants' psychological distress over the past week, scores were summed across the items (Total score ranges from 0-72, with higher scores indicating more stress) (Derogatis, 1975).
Caregiver's Stress Scale has a series of subscales based on a conceptual model of caregivers' stress: overload, relational deprivation, job and caregiving conflict, role captivity, sense of self, caregiving competence, personal gain, management of situation, management of meaning, management of distress, and expressive support. Each subscale ranges from 1 (strongly disagree) to 4 (strongly agree), and each subscale was averaged (with possible score ranging from 1-4) so that higher scores would indicate a higher value.
Overload Pretest
Group
Value
95% CI
Social Exergame Treatment Group
1.84
± 0.92
Control Group
1.61
± 0.68
Overload Posttest
Group
Value
95% CI
Social Exergame Treatment Group
1.77
± 0.80
Control Group
1.58
± 0.73
Relational Deprivation Pretest
Group
Value
95% CI
Social Exergame Treatment Group
1.97
± 0.97
Control Group
1.83
± 0.85
Relational Deprivation Posttest
Group
Value
95% CI
Social Exergame Treatment Group
1.83
± 0.86
Control Group
1.83
± 0.77
Job Caregiving Conflict Pretest
Group
Value
95% CI
Social Exergame Treatment Group
2.18
± 0.72
Control Group
2.11
± 0.60
Job Caregiving Conflict Posttest
Group
Value
95% CI
Social Exergame Treatment Group
2.25
± 0.73
Control Group
2.27
± 0.75
Role Captivity Pretest
Group
Value
95% CI
Social Exergame Treatment Group
1.88
± 0.90
Control Group
1.93
± 0.83
Role Captivity Posttest
Group
Value
95% CI
Social Exergame Treatment Group
1.82
± 1.02
Control Group
2.13
± 1.04
International Physical Activity Questionnaire (IPAQ) Short VersionPrimary· Pretest (before week 1) and posttest (after week 8)
International Physical Activity Questionnaire - Short Version. A continuous score was calculated expressed as MET (Metabolic Equivalents) minutes per week: Total MET-min/week = (Walk METs\*min\*days) + (Mod METs\*min\*days) + Vig METs\*min\*days). A higher score means a higher level of physical activity.
9 items assessed how certain participants will exercise under certain circumstances (e.g., when you are feeling under pressure or when you are away from home). Items are assessed from 1 (very sure) to 4 (not at all sure). Items were reverse coded and summed across all items with a score ranging from 9 to 36. A higher score indicates higher exercise self-efficacy.
Pretest
Group
Value
95% CI
Social Exergame Treatment Group
19.74
± 6.31
Control Group
19.10
± 6.99
Posttest
Group
Value
95% CI
Social Exergame Treatment Group
22.87
± 6.70
Control Group
22.86
± 6.68
Satisfaction With Life ScaleSecondary· Pretest (before week 1) and posttest (after week 8)
Items are assessed from 1 (disagree strongly) to 7 (agree strongly) summed across all items, ranging from 5-35. A higher score indicates a higher satisfaction with life.
Pretest
Group
Value
95% CI
Social Exergame Treatment Group
19.84
± 7.50
Control Group
19.95
± 7.95
Posttest
Group
Value
95% CI
Social Exergame Treatment Group
20.61
± 7.43
Control Group
18.66
± 8.73
Sense of ControlSecondary· Pretest (before week 1) and posttest (after week 8)
items were used to assess sense of control. For example: "There is little I can do to change many of the important things in my life." Items are assessed from 1 (strongly disagree) to 7 (strongly agree) and reverse coded. A sum across all items was calculated ranging from 6-42. A higher score indicates a higher sense of control.
Pretest
Group
Value
95% CI
Social Exergame Treatment Group
31.96
± 6.05
Control Group
29.77
± 6.76
Posttest
Group
Value
95% CI
Social Exergame Treatment Group
31.10
± 7.32
Control Group
29.07
± 7.82
Adverse events — posted to ClinicalTrials.gov
Time frame: 2 months.
Reporting threshold: 0%.
Adverse-event reports describe events observed during the trial — not all are caused by the drug.
The goal of this study is to examine Go\&Grow as a social exergame intervention to increase physical activity and social support, to promote well-being in family caregivers, and to test social support and physical activity as mechanisms for the effects of the intervention.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Brandeis University
Last refreshed: 19 July 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05032872.