Who is sponsoring NCT05031286?

NCT05031286 is sponsored by Balgrist University Hospital.

What drugs are being tested in NCT05031286?

Interventions in NCT05031286: Cutaneous thermal stimuli.

What condition does NCT05031286 study?

NCT05031286 studies Central Sensitisation.

Is NCT05031286 still recruiting?

NCT05031286 is currently completed. Last updated 11 April 2023.

Last reviewed 2023-04-11 · How we verify

NCT05031286

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Differences in Pain Processing Between Men and Women

Completed NA Last updated 11 April 2023

What this trial tests

NA trial testing Cutaneous thermal stimuli in Central Sensitisation in 66 participants. Completed in 31 December 2022.

Timeline

1 May 2021

Primary endpoint
31 December 2022

31 December 2022

Quick facts

Lead sponsor	Balgrist University Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	basic science
Enrollment	66
Start date	1 May 2021
Primary completion	31 December 2022
Estimated completion	31 December 2022
Sites	1 location across Switzerland

Drugs / interventions tested

Cutaneous thermal stimuli

Conditions studied

Central Sensitisation — all drugs for Central Sensitisation →

Sponsor

Balgrist University Hospital

Who can join

Adults 18 to 40, any sex, with Central Sensitisation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Many chronic pain conditions show clear differences between between men and women, such as reported pain intensities or treatment effects, with chronic pain conditions being generally more frequent in women. Yet, the underlying mechanisms causing these differences are poorly understood. Central sensitization (CS) is considered one important mechanism in pain patients which differs between female and male patients. The central hypothesis is that already in the healthy population CS processes are more pronounced in women than in men.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Healthy women show more experimentally induced central sensitization compared with men.
Guekos A, Saxer J, Salinas Gallegos D, Schweinhardt P. · · 2024 · cited 12× · PMID 38231588 · DOI 10.1097/j.pain.0000000000003144

Verify or expand the search:

Other recruiting trials for Central Sensitisation

Currently open trials in the same condition.

NCT06893822 — The Effect of Griffonia Simplicifolia on Pain Intensity, Central and Peripheral Sensitization, Painmodulation in Healthy · NA · recruiting
NCT07109843 — Effect of Boswellia Serrata on Pain Intensity, Central and Peripheral Sensitization, and Pain Modulation in Healthy Volu · NA · recruiting
NCT07114913 — Symptom Distribution and Pain Sensitization in Carpal Tunnel Syndrome · recruiting
NCT06770634 — Investigation of Central Sensitization and Associated Factors in Patients With Lipedema · recruiting
NCT06492148 — Myofascial Release Technique in Women With Primary Dysmenorrhea · NA · recruiting

Other Balgrist University Hospital trials

Trials by the same sponsor.

NCT06813859 — Monitored Effects of Physical Activity on Fetal Heart Rate by Using a Wireless Non-invasive Device · not yet recruiting
NCT06668116 — The Impact of Local Anesthetic Dilution on Possible Blinding for Nerve Blocks · NA · completed
NCT06552195 — Augmented Reality in Learning Anatomy: The TEACHANATOMY Randomized Cross-over Trial · NA · not yet recruiting
NCT06443879 — Loss and Return of Sensation After Axillary Brachial Plexus Nerve Block - Distally or Proximally · completed
NCT06036849 — Linking Physiological Responses to Clinical Outcomes Following Cervical Spine Manipulation · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05031286 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Balgrist University Hospital
Last refreshed: 11 April 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05031286.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing