NCT05029700

The Effects of Trunk Stabilization and Aerobic Trainings in Multiple Sclerosis

Completed NA Last updated 31 August 2021

What this trial tests

NA trial testing Combined exercise training in Physical Therapy in 20 participants. Completed in 1 February 2021.

Timeline

1 June 2019

Primary endpoint
1 December 2020

1 February 2021

Quick facts

Lead sponsor	Ankara Yildirim Beyazıt University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	20
Start date	1 June 2019
Primary completion	1 December 2020
Estimated completion	1 February 2021
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Combined exercise training
• Aerobic training

Conditions studied

• Physical Therapy — all drugs for Physical Therapy →

Sponsor

Ankara Yildirim Beyazıt University

Who can join

Adults 18 to 65, any sex, with Physical Therapy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Balance requires many central nervous system controlled functions, and most or all of these functions can be affected by MS, so balance is very often impaired in patients with MS. Core stability is also decreased in patients with MS. Core stability is among the most important factors that ensure the balance and walking of the participants in different environments and conditions during functional activities. In addition to core muscle activity, lower extremity muscle strength and endurance decrease due to the influence of central nervous system and decrease in physical activity. Functional exercise capacity also decreases due to the influence of the central nervous system and the decrease in physical activity in patients with MS.

Despite all these symptoms and the benefits of exercise training, unfortunately, most MS patients are physically inactive, which can initiate a cycle of deconditioning and worsening of symptoms. In the literature, the combined effects of aerobic training and resistance training have been examined, and it has been stated that combining these two trainings will increase the effectiveness on symptoms. In recent years, trunk stabilization training has started to be included in physiotherapy and rehabilitation programs as an alternative method in patients with MS, based on the knowledge that core stability is effective on many functions and symptoms, as well as aerobic and resistance training. Considering that combined training practices are more effective in reducing symptoms, the investigators think that aerobic training and trunk stabilization training may be more effective in reducing symptoms in patients with MS when applied in combination. In addition, when all these studies were examined, the subtypes of MS patients included in the studies were generally not specified. The effects of these trainings on balance, core stability lower extremity muscle strength and endurance, and functional exercise capacity have not been demonstrated in patients with relapsing remitting MS (RR-MS), the most common type of MS disease. Therefore, the aim of this study is to examine the effects of trunk stabilization training combined with aerobic training on balance, core stability, lower extremity muscle strength and endurance, and functional exercise capacity in patients with RR-MS.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.