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NCT05028868: CRISTINA
Clinical Research of Intravenous Thrombolysis for Ischemic Stroke in Northeast of China
trial in Ischemic Stroke in 500 participants. Status unknown.
28 February 2025
Quick facts
| Lead sponsor | Yi Yang |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 500 |
| Start date | 1 June 2015 |
| Primary completion | 28 February 2025 |
| Estimated completion | 28 January 2026 |
| Sites | 1 location across China |
Conditions studied
- Ischemic Stroke — all drugs for Ischemic Stroke →
- Thrombosis — all drugs for Thrombosis →
Sponsor
Yi Yang — full company profile →
Who can join
18 and older, any sex, with Ischemic Stroke or Thrombosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This research is based on clinic treatment of intravenous thrombolysis for patients with acute ischemic stroke.By building up a database of these patients, the investigators aim to find some significance between groups by analyzing population information, clinical status and such for better evaluation and optimal treatment decision.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Platelet-to-lymphocyte ratio at 24h after thrombolysis is a prognostic marker in acute ischemic stroke patients.
Sun YY, Wang MQ, Wang Y, Sun X, et al · · 2022 · cited 24× · PMID 36225933 · DOI 10.3389/fimmu.2022.1000626 -
Heart Rate Variability Parameter Changes in Patients With Acute Ischemic Stroke Undergoing Intravenous Thrombolysis.
Qu Y, Sun YY, Abuduxukuer R, Si XK, et al · · 2023 · cited 8× · PMID 37232237 · DOI 10.1161/jaha.122.028778 -
External validation of N2H3 nomogram to predict outcomes in patients with acute ischemic stroke treated by intravenous thrombolysis.
Zhang HM, Shen ZD, Qu Y, Zhang P, et al · · 2025 · PMID 40842451 · DOI 10.4103/bc.bc_81_24
Verify or expand the search:
- PubMed search for NCT05028868
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Ischemic Stroke
Currently open trials in the same condition.
- NCT07509645 — Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Post · Phase 3 · recruiting
- NCT07375953 — Repeated Intravenous Thrombolysis for Ischemic Stroke Within 3.0 Hours of Onset With Tenecteplase (RITIS-TNK) · Phase 2 · recruiting
- NCT07375966 — Repeated Intravenous Thrombolysis for Ischemic Stroke With Medium to Large Vessel Occlusion Presenting Within 4.5 Hours · Phase 2 · recruiting
- NCT07491952 — Continuous Dual Aspiration Technique With Zoom System for Stroke · recruiting
- NCT07371455 — A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LWP779 in Healthy Participants · Phase 1 · recruiting
Other Yi Yang trials
Trials by the same sponsor.
- NCT03484936 — Safety and Efficacy of Remote Ischemic Conditioning in Patients With Spontaneous Intracerebral Hemorrhage · NA · not yet recruiting
- NCT07042490 — Efficacy and Safety of Plasma Adsorption Combined With EVT for AIS-LVO · NA · not yet recruiting
- NCT03669653 — Safety and Efficacy of Remote Ischemic Conditioning in Patients With Acute Ischemic Stroke · NA · not yet recruiting
- NCT05743101 — Safety and Efficacy Study of Levofloxacin Combined With Endovascular Thrombectomy for Acute Ischemic Stroke · NA · not yet recruiting
- NCT06941961 — iTBS for Acute Ischemic Stroke After Thrombectomy · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05028868 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yi Yang
- Last refreshed: 1 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05028868.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing