Last reviewed · How we verify

NCT05028517

Efficacy Trial of the FMF Connect Mobile Health Intervention

Completed NA Results posted Last updated 14 January 2026
What this trial tests

NA trial testing FMF Connect in Fetal Alcohol Spectrum Disorders in 129 participants. Completed in 31 December 2022.

Timeline
6 January 2022
Primary endpoint
31 December 2022
31 December 2022

Quick facts

Lead sponsorUniversity of Rochester
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposetreatment
Enrollment129
Start date6 January 2022
Primary completion31 December 2022
Estimated completion31 December 2022
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Rochester

Who can join

18 and older, any sex, with Fetal Alcohol Spectrum Disorders. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Eyberg Child Behavior Inventory - Intensity at Baseline and 12-week Follow-Up Primary · baseline to 12 weeks

The Eyberg Child Behavior Inventory measures the intensity of child behavior problems. Scores are presented as T-scores with a mean of 50 and a standard deviation of 10. A T-score of 60 or higher is considered clinically significant. Higher scores indicate more intense behavior problems.

Baseline
GroupValue95% CI
FMF Connect Intervention + Coaching68.33± 1.65
FMF Connect Intervention (no Coaching)69.13± 1.88
Waitlist Comparison Group68.40± 1.65
12-week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching64.47± 1.67
FMF Connect Intervention (no Coaching)65.87± 1.90
Waitlist Comparison Group66.03± 1.67
Reasons for Children's Behavior - Sensory Avoid Subscale at Baseline, 6-Weeks, and 12-Weeks Primary · baseline, 6 weeks, 12 weeks

The Reasons for Children's Behavior measure assesses parents attributions of behavior. It contains 7 total scales. This Sensory Avoid scale measures attributions of behavior based on sensory avoidance. It ranges from 5 to 30 with higher scores reflecting greater agreement with neurodevelopmental attributions.

Baseline
GroupValue95% CI
FMF Connect Intervention + Coaching15.54± 1.02
FMF Connect Intervention (no Coaching)18.91± 1.17
Waitlist Comparison Group16.57± 1.01
6-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching15.87± 1.25
FMF Connect Intervention (no Coaching)19.29± 1.45
Waitlist Comparison Group18.25± 1.25
12-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching15.43± 1.29
FMF Connect Intervention (no Coaching)17.29± 1.49
Waitlist Comparison Group17.57± 1.29
Reasons for Children's Behavior - Sensory Seek Subscale at Baseline, 6-Weeks, and 12-Weeks Primary · baseline, 6 weeks, 12 weeks

The Reasons for Children's Behavior measure assesses parents attributions of behavior. It contains 7 total scales. This Sensory Seek scale measures attributions of behavior based on sensory seeking. It ranges from 5 to 30 with higher scores reflecting greater agreement with neurodevelopmental attributions.

Baseline
GroupValue95% CI
FMF Connect Intervention + Coaching23.79± 1.06
FMF Connect Intervention (no Coaching)23.24± 1.23
Waitlist Comparison Group23.29± 1.06
6-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching23.36± 1.02
FMF Connect Intervention (no Coaching)25.43± 1.17
Waitlist Comparison Group24.39± 1.02
12-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching22.61± 1.19
FMF Connect Intervention (no Coaching)24.76± 1.37
Waitlist Comparison Group23.14± 1.19
Reasons for Children's Behavior - Task Willful Subscale at Baseline, 6-Weeks, and 12-Weeks Primary · baseline, 6 weeks, 12 weeks

The Reasons for Children's Behavior measure assesses parents attributions of behavior. It contains 7 total scales. This Task Willful scale measures attributions of behavior based on willful task avoidance. It ranges from 3 to 18 with higher scores reflecting greater agreement with willful attributions.

Baseline
GroupValue95% CI
FMF Connect Intervention + Coaching10.14± 0.576
FMF Connect Intervention (no Coaching)10.67± 0.665
Waitlist Comparison Group10.43± 0.576
6-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching9.18± 0.527
FMF Connect Intervention (no Coaching)9.86± 0.608
Waitlist Comparison Group10.89± 0.527
12-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching8.93± 0.576
FMF Connect Intervention (no Coaching)8.57± 0.665
Waitlist Comparison Group10.46± 0.576
Reasons for Children's Behavior - Task Ability Subscale at Baseline, 6-Weeks, and 12-Weeks Primary · baseline, 6 weeks, 12 weeks

The Reasons for Children's Behavior measure assesses parents attributions of behavior. It contains 7 total scales. This Task Ability scale measures attributions of behavior based on ability to complete tasks. It ranges from 5 to 30 with higher scores reflecting greater agreement with neurodevelopmental attributions.

Baseline
GroupValue95% CI
FMF Connect Intervention + Coaching23.29± 0.847
FMF Connect Intervention (no Coaching)22.48± 0.978
Waitlist Comparison Group24.32± 0.847
6-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching22.75± 0.746
FMF Connect Intervention (no Coaching)22.77± 0.862
Waitlist Comparison Group24.57± 0.746
12-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching23.00± 0.922
FMF Connect Intervention (no Coaching)21.57± 1.07
Waitlist Comparison Group23.68± 0.922
Reasons for Children's Behavior - Disruptive Behavior Subscale at Baseline, 6-Weeks, and 12-Weeks Primary · baseline, 6 weeks, 12 weeks

The Reasons for Children's Behavior measure assesses parents attributions of behavior. It contains 7 total scales. This Disruptive Behavior scale measures attributions of behavior based on purposeful disruptive behavior. It ranges from 5 to 30 with higher scores reflecting greater agreement with willful attributions.

Baseline
GroupValue95% CI
FMF Connect Intervention + Coaching14.96± 1.28
FMF Connect Intervention (no Coaching)17.05± 1.47
Waitlist Comparison Group15.29± 1.28
6-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching12.36± 1.17
FMF Connect Intervention (no Coaching)13.81± 1.35
Waitlist Comparison Group15.50± 1.17
12 Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching12.07± 1.25
FMF Connect Intervention (no Coaching)13.24± 1.45
Waitlist Comparison Group14.75± 1.25
Reasons for Children's Behavior - Emotional Support Subscale at Baseline, 6-Weeks, and 12-Weeks Primary · baseline, 6 weeks, 12 weeks

The Reasons for Children's Behavior measure assesses parents attributions of behavior. It contains 7 total scales. This Emotional Support scale measures attributions of behavior based on need for emotional support. It ranges from 4 to 24 with higher scores reflecting greater agreement with neurodevelopmental attributions.

Baseline
GroupValue95% CI
FMF Connect Intervention + Coaching19.50± 0.744
FMF Connect Intervention (no Coaching)20.29± 0.859
Waitlist Comparison Group20.79± 0.744
6-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching20.00± 0.603
FMF Connect Intervention (no Coaching)21.43± 0.697
Waitlist Comparison Group21.43± 0.603
12-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching19.89± 0.636
FMF Connect Intervention (no Coaching)20.91± 0.735
Waitlist Comparison Group21.32± 0.636
Reasons for Children's Behavior - Dysregulated Behavior Subscale at Baseline, 6-Weeks, and 12-Weeks Primary · baseline, 6 weeks, 12 weeks

The Reasons for Children's Behavior measure assesses parents attributions of behavior. It contains 7 total scales. This Dysregulated Behavior scale measures attributions of behavior based on dysregulated behavior. It ranges from 3 to 18 with higher scores reflecting greater agreement with neurodevelopmental attributions.

Baseline
GroupValue95% CI
FMF Connect Intervention + Coaching8.36± .709
FMF Connect Intervention (no Coaching)9.48± .819
Waitlist Comparison Group8.964± .709
6-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching9.43± .681
FMF Connect Intervention (no Coaching)10.76± .786
Waitlist Comparison Group10.18± .681
12-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching8.00± .717
FMF Connect Intervention (no Coaching)9.38± .828
Waitlist Comparison Group9.464± .717
Parenting Sense of Competence - Efficacy Sub-scale Baseline, 6-Week, and 12-Week Follow-up Primary · baseline, 6 weeks, 12 weeks

The Parenting sense of competence scale includes two sub-scales: 1) satisfaction and 2) efficacy. The efficacy sub-scale reported here measures how effective parents feel they are and includes 7 items, rated on a scale from 1 ("strongly agree") to 6 ("strongly disagree"). Responses are summed, with possible sub-scale score range from 7 to 42 with higher scores indicating lower feelings of efficacy.

Baseline
GroupValue95% CI
FMF Connect Intervention + Coaching26.86± 1.16
FMF Connect Intervention (no Coaching)26.25± 1.37
Waitlist Comparison Group25.32± 1.16
6-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching27.36± 1.15
FMF Connect Intervention (no Coaching)27.15± 1.37
Waitlist Comparison Group25.50± 1.15
12-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching28.39± 1.14
FMF Connect Intervention (no Coaching)29.30± 1.35
Waitlist Comparison Group26.71± 1.14
Parenting Sense of Competence - Satisfaction Sub-scale at Baseline, 6-Week, 12-Week Follow-up Primary · baseline, 6 weeks, 12 weeks

The Parenting sense of competence scale includes two sub-scales: 1) satisfaction and 2) efficacy. The satisfaction sub-scale reported here includes 9 items, rated on a scale from 1 ("strongly agree") to 6 ("strongly disagree"). Responses are summed, with possible sub-scale score range from 9 to 54 with higher scores indicating higher satisfaction in the parenting role.

Baseline
GroupValue95% CI
FMF Connect Intervention + Coaching35.36± 1.43
FMF Connect Intervention (no Coaching)32.25± 1.70
Waitlist Comparison Group33.14± 1.43
6-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching36.43± 1.27
FMF Connect Intervention (no Coaching)35.20± 1.50
Waitlist Comparison Group32.68± 1.27
12-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching35.89± 1.39
FMF Connect Intervention (no Coaching)36.15± 1.65
Waitlist Comparison Group32.82± 1.39
Family Needs Questionnaire Baseline to 12-Week Follow-up Primary · baseline to 12 weeks

The family needs questionnaire measures the degree to which family needs are met. The scale includes 18 items reflecting family needs that are rated on a scale from 0 to 4, with 0 being not applicable to 4 being met a great deal. The total score on this measure is created by summing across all items. Total score ranges from 0-72. Higher scores reflect more needs being met.

Baseline
GroupValue95% CI
FMF Connect Intervention + Coaching40.63± 1.79
FMF Connect Intervention (no Coaching)37.18± 2.09
Waitlist Comparison Group37.93± 1.82
12-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching48.47± 2.07
FMF Connect Intervention (no Coaching)47.00± 2.42
Waitlist Comparison Group42.38± 2.11
FASD Knowledge at Baseline and 12-Week Follow-up Primary · baseline to 12 weeks

The Knowledge and Advocacy questionnaire assesses caregiver knowledge about FASD and advocacy and ranges from 0 to 28. Higher scores reflect greater knowledge.

Baseline
GroupValue95% CI
FMF Connect Intervention + Coaching20.97± .521
FMF Connect Intervention (no Coaching)21.41± .609
Waitlist Comparison Group20.73± .521
12-Week Follow-up
GroupValue95% CI
FMF Connect Intervention + Coaching21.30± .566
FMF Connect Intervention (no Coaching)22.36± .661
Waitlist Comparison Group20.30± .566

Sponsor's own description

The purpose of this study is to test a new smartphone "app" for parents/caregivers of children with fetal alcohol spectrum disorder (FASD). The app is called Families Moving Forward (FMF) Connect. The goal of the app is to provide parents/caregivers with useful information to help manage their children's condition and obtain peer support.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Psychosocial and medication interventions to stop or reduce alcohol consumption during pregnancy.
    Minozzi S, Ambrosi L, Saulle R, Uhm SS, et al · · 2024 · cited 6× · PMID 38682758 · DOI 10.1002/14651858.cd015042.pub2

Verify or expand the search:

Other trials of FMF Connect

Trials testing the same drug.

Other recruiting trials for Fetal Alcohol Spectrum Disorders

Currently open trials in the same condition.

Other University of Rochester trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05028517.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing