Who is sponsoring NCT05027685?

NCT05027685 is sponsored by ReCor Medical, Inc..

What drugs are being tested in NCT05027685?

Interventions in NCT05027685: The Paradise Ultrasound Renal Denervation System.

What condition does NCT05027685 study?

NCT05027685 studies Hypertension.

Is NCT05027685 still recruiting?

NCT05027685 is currently recruiting now. Last updated 7 July 2023.

Last reviewed 2023-07-07 · How we verify

NCT05027685: GPS Registry

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The "Global Paradise System" Registry

Recruiting now Last updated 7 July 2023

What this trial tests

trial testing The Paradise Ultrasound Renal Denervation System in Hypertension in 3,000 participants. Currently enrolling.

Timeline

13 January 2022

Primary endpoint
31 December 2030

31 December 2031

Quick facts

Lead sponsor	ReCor Medical, Inc.
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	3,000
Start date	13 January 2022
Primary completion	31 December 2030
Estimated completion	31 December 2031
Sites	35 locations across France, Netherlands, Belgium, United Kingdom, Germany, Monaco, Switzerland

Drugs / interventions tested

The Paradise Ultrasound Renal Denervation System

Conditions studied

Hypertension — all drugs for Hypertension →

Sponsor

ReCor Medical, Inc.

Who can join

18 and older, any sex, with Hypertension. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The GPS Registry is a multi-centre, single-arm, non-interventional (observational) registry. In addition to collecting data from patients treated as per standard clinical practice, the Registry will also regularly collect telemetric Home Blood Pressure (HBP) measurements and Patient Reported Outcome (PRO) data via a standardized quality of life questionnaire. The objective of the GPS Registry is to document the long-term safety and effectiveness of the commercially available Paradise Ultrasound Renal Denervation System when used per its labelling in patients deemed to be candidates for RDN as per physician's assessment.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Advances in pathogenesis and treatment of essential hypertension.
Ma J, Chen X. · · 2022 · cited 29× · PMID 36312252 · DOI 10.3389/fcvm.2022.1003852
Real-world experience with ultrasound renal denervation utilizing home blood pressure monitoring: the Global Paradise System registry study design.
Mahfoud F, Azizi M, Daemen J, Sharp ASP, et al · · 2024 · cited 15× · PMID 37943324 · DOI 10.1007/s00392-023-02325-x
Renal Denervation for Hypertension: The Current Landscape and Future Directions.
Fulton B, Giri J, Rader F, Cohen DL, et al · · 2024 · cited 2× · PMID 39006469 · DOI 10.17925/hi.2024.18.1.2

Verify or expand the search:

Other recruiting trials for Hypertension

Currently open trials in the same condition.

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NCT07238556 — A Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors · NA · recruiting
NCT07238400 — Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia · Phase 2 · recruiting
NCT07135505 — Early Time-Restricted Eating in Older Adults With Hypertension · NA · recruiting

Other ReCor Medical, Inc. trials

Trials by the same sponsor.

NCT07231757 — The RADIANCE CED Study · recruiting
NCT05017935 — RADIANCE Continued Access Protocol · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05027685 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by ReCor Medical, Inc.
Last refreshed: 7 July 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05027685.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing