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NCT05027347

Detection of Plasma Circulating Tumor DNA in Gastric Cancer

Status unknown Last updated 28 April 2022
What this trial tests

trial testing plasma circulating tumor DNA in Circulating Tumor DNA (ctDNA) in 200 participants. Status unknown.

Timeline
10 October 2021
Primary endpoint
30 September 2023
30 September 2023

Quick facts

Lead sponsorUniversity Medical Center Ho Chi Minh City (UMC)
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment200
Start date10 October 2021
Primary completion30 September 2023
Estimated completion30 September 2023
Sites1 location across Vietnam

Drugs / interventions tested

Conditions studied

Sponsor

University Medical Center Ho Chi Minh City (UMC)

Who can join

18 and older, any sex, with Circulating Tumor DNA (ctDNA) or Gastric Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to develop a protocol for detection of circulating tumor DNA (ctDNA) in plasma of patients with early stages of gastric cancer.

Publications & conference data

7 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Liquid biopsy in gastric cancer: predictive and prognostic biomarkers.
    Zhang Z, Wu H, Chong W, Shang L, et al · · 2022 · cited 84× · PMID 36302755 · DOI 10.1038/s41419-022-05350-2
  2. Novel biomarkers for early detection of gastric cancer.
    Matsuoka T, Yashiro M. · · 2023 · cited 60× · PMID 37213407 · DOI 10.3748/wjg.v29.i17.2515
  3. Research progress of CTC, ctDNA, and EVs in cancer liquid biopsy.
    Wang X, Wang L, Lin H, Zhu Y, et al · · 2024 · cited 54× · PMID 38333685 · DOI 10.3389/fonc.2024.1303335
  4. The Role of ctDNA in Gastric Cancer.
    Mencel J, Slater S, Cartwright E, Starling N. · · 2022 · cited 26× · PMID 36291888 · DOI 10.3390/cancers14205105
  5. Clinical applications and perspectives of circulating tumor DNA in gastric cancer.
    Li JH, Zhang DY, Zhu JM, Dong L. · · 2024 · cited 14× · PMID 38184573 · DOI 10.1186/s12935-024-03209-4
  6. Current Applications of Liquid Biopsy in Gastrointestinal Cancer Disease-From Early Cancer Detection to Individualized Cancer Treatment.
    David P, Mittelstädt A, Kouhestani D, Anthuber A, et al · · 2023 · cited 10× · PMID 37046585 · DOI 10.3390/cancers15071924
  7. Next-Generation Sequencing-Based Molecular Profiling Using Cell-Free DNA: A Valuable Tool for the Diagnostic and Prognostic Evaluation of Patients With Gastric Cancer.
    Jang MA. · · 2024 · cited 1× · PMID 37880993 · DOI 10.3343/alm.2023.0391

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