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NCT05022290
Double-syringe vs Single-syringe Technique of Adenosine for Termination of Regular Narrow Complex Tachycardia
NA trial testing Single-syringe diluted with normal saline technique in Supraventricular Tachycardia in 300 participants. Status unknown.
31 December 2024
Quick facts
| Lead sponsor | Khon Kaen University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 300 |
| Start date | 1 October 2020 |
| Primary completion | 31 December 2024 |
| Estimated completion | 30 June 2025 |
| Sites | 1 location across Thailand |
Drugs / interventions tested
- Single-syringe diluted with normal saline technique
Conditions studied
- Supraventricular Tachycardia — all drugs for Supraventricular Tachycardia →
Sponsor
Khon Kaen University
Who can join
Adults 18 to 80, any sex, with Supraventricular Tachycardia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Adenosine has been discovered since 1929 and used in the acute treatment of arrhythmias. It uses as a therapeutic diagnosis in patients with regular narrow QRS complex tachyarrhythmias. The conventional method of adenosine administration is the double syringe technique (DST). However, it consumes a lot of resources including two syringes, a stopcock, an extension tube, and needs 2 nurses to administer. An observational study found that a single syringe technique (adenosine diluted with normal saline up to 20 ml) was as effective as a double syringe technique. However, there is no randomized control trial for proving its efficacy.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparison between the double-syringe and the single-syringe techniques of adenosine administration for terminating supraventricular tachycardia: A pilot, randomized controlled trial.
Kotruchin P, Chaiyakhan IO, Kamonsri P, Chantapoh W, et al · · 2022 · cited 10× · PMID 35340059 · DOI 10.1002/clc.23820
Verify or expand the search:
- PubMed search for NCT05022290
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05022290 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Khon Kaen University
- Last refreshed: 17 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05022290.
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