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NCT05021588: SARS-CoV-2
Steroid and Anticoagulant Therapy in covid19
NA trial testing steroid and anticoagulants according to different protocols. in Pneumonia, Viral in 123 participants. Completed in 10 September 2020.
2 August 2020
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 123 |
| Start date | 12 April 2020 |
| Primary completion | 2 August 2020 |
| Estimated completion | 10 September 2020 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- steroid and anticoagulants according to different protocols.
Conditions studied
- Pneumonia, Viral — all drugs for Pneumonia, Viral →
Sponsor
Assiut University
Who can join
Eligibility, any sex, with Pneumonia, Viral. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
As COVID-19 has neither standard treatment protocol nor guidelines, there are many treatment protocols foranti-inflammatory corticosteroids and anti-coagulations for severe COVID-19 pneumonia patients. This study aimed to assess the most suitable modality in this high-risk group. Methods: A prospective, experimental study design was adopted, that included 123 severe COVID-19 pneumonia patientsadmitted at Assiut UniversityHospital from April 10th, 2020, to September10th, 2020. Patients were divided into 3 groups according to a combined corticosteroid and anticoagulants therapy protocols. Group A included 32 patients, group B included 45 patients, and group C included 46 patients. Assessment of cases was conducted according to the treatment type and duration, weaning duration from oxygen therapy, length of hospital and ICU stay, and complications during treatment.Three months follow up after discharge was performed.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Challenges in Steroid and Anticoagulant Therapy in Severe COVID-19 Pneumonia: A Prospective Study.
Hassan AT, Elmoniem AEA, Abdelrady MM, Mohamed ME, et al · · 2021 · cited 5× · PMID 34680795 · DOI 10.3390/antibiotics10101214
Verify or expand the search:
- PubMed search for NCT05021588
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Pneumonia, Viral
Currently open trials in the same condition.
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Other Assiut University trials
Trials by the same sponsor.
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- NCT07273214 — Knowledge, Attitude and Practice of Third Trimester Pregnant Mothers Towards Self-Medication in Assiut, Egypt · not yet recruiting
- NCT07194863 — Efficacy of Essential Phospholipid Versus Betaine HCL/L-Glutamic Acid in MAFLD · not yet recruiting
- NCT07053709 — Screening for Hyperuricemia in Patients With Metabolic Associated Fatty Liver Disease (MAFLD) · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05021588 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 25 August 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05021588.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing