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NCT05021588: SARS-CoV-2

Steroid and Anticoagulant Therapy in covid19

Completed NA Last updated 25 August 2021
What this trial tests

NA trial testing steroid and anticoagulants according to different protocols. in Pneumonia, Viral in 123 participants. Completed in 10 September 2020.

Timeline
12 April 2020
Primary endpoint
2 August 2020
10 September 2020

Quick facts

Lead sponsorAssiut University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingtriple
Primary purposetreatment
Enrollment123
Start date12 April 2020
Primary completion2 August 2020
Estimated completion10 September 2020
Sites1 location across Egypt

Drugs / interventions tested

Conditions studied

Sponsor

Assiut University

Who can join

Eligibility, any sex, with Pneumonia, Viral. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

As COVID-19 has neither standard treatment protocol nor guidelines, there are many treatment protocols foranti-inflammatory corticosteroids and anti-coagulations for severe COVID-19 pneumonia patients. This study aimed to assess the most suitable modality in this high-risk group. Methods: A prospective, experimental study design was adopted, that included 123 severe COVID-19 pneumonia patientsadmitted at Assiut UniversityHospital from April 10th, 2020, to September10th, 2020. Patients were divided into 3 groups according to a combined corticosteroid and anticoagulants therapy protocols. Group A included 32 patients, group B included 45 patients, and group C included 46 patients. Assessment of cases was conducted according to the treatment type and duration, weaning duration from oxygen therapy, length of hospital and ICU stay, and complications during treatment.Three months follow up after discharge was performed.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Challenges in Steroid and Anticoagulant Therapy in Severe COVID-19 Pneumonia: A Prospective Study.
    Hassan AT, Elmoniem AEA, Abdelrady MM, Mohamed ME, et al · · 2021 · cited 5× · PMID 34680795 · DOI 10.3390/antibiotics10101214

Verify or expand the search:

Other recruiting trials for Pneumonia, Viral

Currently open trials in the same condition.

Other Assiut University trials

Trials by the same sponsor.

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