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NCT05019092

Systematic Screening for Deep Vein Thrombosis in Critically Ill Patients

Status unknown NA Last updated 24 August 2021
What this trial tests

NA trial testing Ultrasound examination of lower limb veins in Deep Vein Thrombosis in 100 participants. Status unknown.

Timeline
1 January 2021
Primary endpoint
30 June 2021
31 December 2021

Quick facts

Lead sponsorEttore Marini
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposescreening
Enrollment100
Start date1 January 2021
Primary completion30 June 2021
Estimated completion31 December 2021
Sites1 location across Italy

Drugs / interventions tested

Conditions studied

Sponsor

Ettore Marini

Who can join

18 and older, any sex, with Deep Vein Thrombosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: venous thromboembolism (VTE) is a common complication in critically ill patients, admitted to the Intensive Care Units (ICUs). At the present time, there is no validated score to estimate risks and benefits of antithrombotic pharmacological prophylaxis in this subset of patients. Aim of the study: investigating potential harms and benefits of a protocol for systematic screening of DVT in critically ill patients, admitted to an ICU. Expected relevance: systematic screening for deep vein thrombosis (DVT) through ultrasound (US) lower limb veins examination could help defining the indication to antithrombotic pharmacological treatment, but no protocol of systematic screening has been validated so far. Furthermore, the screening could be associated with over-diagnosis and consequent over-treatment, as well as increased management burden for the caregivers and higher healthcare costs.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Ultrasound screening for asymptomatic deep vein thrombosis in critically ill patients: a pilot trial.
    Tini G, Moriconi A, Ministrini S, Zullo V, et al · · 2022 · cited 4× · PMID 36044159 · DOI 10.1007/s11739-022-03085-8

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