Who is sponsoring NCT05016726?

NCT05016726 is sponsored by SS Annunziata Hospital, Savigliano.

What drugs are being tested in NCT05016726?

Interventions in NCT05016726: Intravascular Lithotripsy.

What condition does NCT05016726 study?

NCT05016726 studies Coronary Artery Disease, Myocardial Infarction.

Is NCT05016726 still recruiting?

NCT05016726 is currently status unknown. Last updated 23 August 2021.

Last reviewed 2021-08-23 · How we verify

NCT05016726: ROLLING-STONE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intravascular Lithotripsy and/or Mechanical Debulking for Severely Calcified Coronary Artery Lesions

Status unknown Last updated 23 August 2021

What this trial tests

trial testing Intravascular Lithotripsy in Coronary Artery Disease in 400 participants. Status unknown.

Timeline

1 October 2021

Primary endpoint
1 October 2023

30 October 2024

Quick facts

Lead sponsor	SS Annunziata Hospital, Savigliano
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	400
Start date	1 October 2021
Primary completion	1 October 2023
Estimated completion	30 October 2024

Drugs / interventions tested

Intravascular Lithotripsy

Conditions studied

Coronary Artery Disease — all drugs for Coronary Artery Disease →
Myocardial Infarction — all drugs for Myocardial Infarction →

Sponsor

SS Annunziata Hospital, Savigliano

Who can join

18 and older, any sex, with Coronary Artery Disease or Myocardial Infarction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To evaluate intra-procedural and long-term effects of intravascular lithotripsy with the ShockWave System and/or non-balloon mechanical debulking devices, prior and/or after coronary stenting in an angiographically well-defined group of patients with complex calcified coronary artery lesions.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

SCAI Expert Consensus Statement on the Management of Calcified Coronary Lesions.
Riley RF, Patel MP, Abbott JD, Bangalore S, et al · · 2024 · cited 58× · PMID 39132214 · DOI 10.1016/j.jscai.2023.101259
The Significance of Coronary Artery Calcification for Percutaneous Coronary Interventions.
Lis P, Rajzer M, Klima Ł. · · 2024 · cited 1× · PMID 38470631 · DOI 10.3390/healthcare12050520
Intravascular Lithotripsy or Mechanical Debulking in Complex Calcified Coronary Arteries: Multicenter, Prospective ROLLING STONE Study.
Cerrato E, Pavani M, Zecchino S, Leoncini M, et al · · 2026 · PMID 41609534 · DOI 10.1016/j.jcin.2025.11.033

Verify or expand the search:

Other trials of Intravascular Lithotripsy

Trials testing the same drug.

NCT07109479 — Safety and Effectiveness of the Single-Use Coronary Forward Intravascular Lithotripsy Catheter Combined With the Intrava · NA · not yet recruiting
NCT06238518 — Intravascular Lithotripsy Versus Conventional Therapy for Severely Calcified Coronary Artery Lesions · NA · unknown
NCT06089135 — Shockwave Lithoplasty Compared to Cutting Balloon Treatment in Calcified Coronary Disease - A Randomized Controlled Tria · NA · completed
NCT05858905 — FORWARD PAD IDE Study With the Shockwave Javelin IVL Catheter · NA · completed
NCT05662787 — BOLT Lithotripsy RESTORE ATK Trial · NA · completed

Other recruiting trials for Coronary Artery Disease

Currently open trials in the same condition.

NCT07399002 — LONG NAGOMI™ PMCF STUDY · recruiting
NCT07420582 — Antegrade Autologous Blood Reinfusion After CPB · recruiting
NCT07493603 — A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart Disease · Phase 1, PHASE2 · recruiting
NCT06535568 — Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO · NA · recruiting
NCT07286578 — A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Under · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05016726 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by SS Annunziata Hospital, Savigliano
Last refreshed: 23 August 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05016726.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing