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NCT05016557: SCAM
The Muscle Protein Synthetic Response of Algal and Fungal Protein
NA trial testing Protein ingestion in Muscle Metabolism in 36 participants. Completed in 24 June 2022.
24 June 2022
Quick facts
| Lead sponsor | University of Exeter |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | basic science |
| Enrollment | 36 |
| Start date | 19 December 2020 |
| Primary completion | 24 June 2022 |
| Estimated completion | 24 June 2022 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Protein ingestion
Conditions studied
- Muscle Metabolism — all drugs for Muscle Metabolism →
Sponsor
University of Exeter
Who can join
Adults 18 to 40, any sex, with Muscle Metabolism. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Dietary protein intake is vital for the maintenance of skeletal muscle mass and health. The production of animal-based proteins sources is associated with growing environmental and ethical challenges. As such, sustainable alternatives are needed. Algae are sustainably produced high-protein sources and it is predicted that algae will become one of the most consumed proteins in the next decades. However, the effects of algae on the stimulation of muscle mass growth are unknown. Therefore, we aim to assess the rate of digestion and absorption, and the effects on muscle growth of two types of algae (spirulina and chlorella) when compared to a sustainable non-animal derived fungal reference protein (mycoprotein), a source known to elicit a robust anabolic response.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Algae Ingestion Increases Resting and Exercised Myofibrillar Protein Synthesis Rates to a Similar Extent as Mycoprotein in Young Adults.
van der Heijden I, West S, Monteyne AJ, Finnigan TJA, et al · · 2023 · cited 13× · PMID 37716611 · DOI 10.1016/j.tjnut.2023.08.035
Verify or expand the search:
- PubMed search for NCT05016557
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Protein ingestion
Trials testing the same drug.
- NCT04297137 — The Bioavailability of Multiple Novel, Sustainable, Non-animal Derived Protein Sources · NA · completed
- NCT03147001 — Protein Ingestion Before Training Low · NA · completed
Other University of Exeter trials
Trials by the same sponsor.
- NCT07457437 — Function and Lean Mass Preservation With Resistance Exercise During a GLP-1RA Treatment · NA · recruiting
- NCT06478121 — Understanding Beta Cell Disorders Through the Study of Rare Genotypes (ENDURE) · recruiting
- NCT06965699 — The Effect of a Plant-based, Protein-dense Sauce on Essential Amino Acid Concentrations and Gut Fullness in Older Adults · NA · recruiting
- NCT06846294 — Obesity Prevention in Children and Young People Treated for Acute Lymphoblastic Leukaemia with ALLTogether · NA · not yet recruiting
- NCT06852547 — The Effect of Ingesting a Novel Algae Protein Source on Rested and Exercised Muscle Protein Synthesis Rates in Older Adu · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05016557 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Exeter
- Last refreshed: 11 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05016557.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing