NCT05010382 is a NA clinical trial of Implant placement surgery in Marginal Bone Loss, sponsored by Universidad Complutense de Madrid.

Who is sponsoring NCT05010382?

NCT05010382 is sponsored by Universidad Complutense de Madrid.

What drugs are being tested in NCT05010382?

Interventions in NCT05010382: Implant placement surgery.

What condition does NCT05010382 study?

NCT05010382 studies Marginal Bone Loss.

Is NCT05010382 still recruiting?

NCT05010382 is currently completed. Last updated 18 August 2021.

Last reviewed 2021-08-18 · How we verify

NCT05010382

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy of Implant Surface Characteristics in Patients With History of Periodontitis

Completed NA Last updated 18 August 2021

What this trial tests

NA trial testing Implant placement surgery in Marginal Bone Loss in 40 participants. Completed in 25 July 2021.

Timeline

13 March 2018

Primary endpoint
25 July 2021

25 July 2021

Quick facts

Lead sponsor	Universidad Complutense de Madrid
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	40
Start date	13 March 2018
Primary completion	25 July 2021
Estimated completion	25 July 2021
Sites	1 location across Spain

Drugs / interventions tested

Implant placement surgery

Conditions studied

Marginal Bone Loss — all drugs for Marginal Bone Loss →

Sponsor

Universidad Complutense de Madrid — full company profile →

Who can join

20 and older, any sex, with Marginal Bone Loss. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to evaluate in patients with history of periodontitis the clinical, microbiological and radiological outcomes of implants with a modified implant design consisting on a machined surface in the coronal third of the implant. In this 12-month, parallel-arm, randomized controlled trial, patients with history of treated periodontitis and in need of dental implants for single-unit or short edentulous spaces (i.e. two implants) will be randomly assigned to a test group (implants with a hybrid surface, presenting a machined coronal third; HS) or a control group (conventional moderately rough implants; RS). Implants will be restored 3 months later with fixed implant supported reconstructions. Radiological, clinical, microbiological and patient-related outcome measures (PROMs) will be assessed 3, 6 and 12 months after the prosthetic installation.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

One-year outcomes of dental implants with a hybrid surface macro-design placed in patients with history of periodontitis: A randomized clinical trial.
Serrano B, Sanz-Sánchez I, Serrano K, Montero E, et al · · 2022 · cited 12× · PMID 34881442 · DOI 10.1111/jcpe.13575
Three-Year Outcomes of Dental Implants With a Hybrid Surface Macro-Design Placed in Patients With History of Periodontitis: A Randomised Clinical Trial.
Serrano B, Sanz-Sánchez I, Montero E, Sanz M. · · 2025 · cited 3× · PMID 40277088 · DOI 10.1111/jcpe.14153
Three-dimensional niche-like porous structure locoregionally regulating macrophage immunosenescence rejuvenates aged bone repair.
Zhao DW, Fei X, Zhai H, Zhang Y, et al · · 2026 · PMID 41909511 · DOI 10.1016/j.bioactmat.2026.03.028

Verify or expand the search:

Other recruiting trials for Marginal Bone Loss

Currently open trials in the same condition.

NCT07107464 — Subcrestal vs Juxtacrestal PRAMA Implants With Variable Necks · NA · active not recruiting

Other Universidad Complutense de Madrid trials

Trials by the same sponsor.

NCT07361848 — Long-Hold Yielding Isometric Exercise for Patellar Tendinopathy in Weightlifting Athletes · NA · not yet recruiting
NCT07273006 — Percutaneous Electrical Nerve Stimulation As Alternative To Nerve Blocks In Anesthesia, Pain Medicine And Rehabilitation · Phase 4 · not yet recruiting
NCT07527351 — ANALYSIS OF THE RELIABILITY AND VALIDITY OF LASER SPECKLE CONTRAST IMAGING · NA · recruiting
NCT07484620 — Physical Activity and Fitness in Pediatric Inflammatory Bowel Disease · NA · not yet recruiting
NCT07485400 — Aerobic Interval vs Continuous Training on Heart Rate-Power Decoupling in Ischemic Heart Disease · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05010382 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universidad Complutense de Madrid
Last refreshed: 18 August 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05010382.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing