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NCT05010291
Behavioural Text Messages to Improve Retention in Care in South Africa
NA trial testing Standard of Care (SOC) text message reminder to attend clinic appointment in HIV/AIDS in 1,541 participants. Completed in 7 December 2021.
7 December 2021
Quick facts
| Lead sponsor | University of Pennsylvania |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | screening |
| Enrollment | 1,541 |
| Start date | 5 August 2021 |
| Primary completion | 7 December 2021 |
| Estimated completion | 7 December 2021 |
| Sites | 1 location across South Africa |
Drugs / interventions tested
- Standard of Care (SOC) text message reminder to attend clinic appointment
- Loss aversion framed text message reminder to attend clinic appointment
- Social norms framed text message reminder to attend clinic appointment
- Altruism framed text message reminder to attend clinic appointment
Conditions studied
- HIV/AIDS — all drugs for HIV/AIDS →
Sponsor
University of Pennsylvania
Who can join
18 and older, any sex, with HIV/AIDS. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The proportion of South Africans aware of their HIV status and on treatment remains lower than optimal. The goal of this study is to rapidly determine whether text messages framed according to behavioural economics principles increase clinic attendance among recipients of care on antiretroviral therapy in South Africa. We hypothesize that messages incorporating behavioural economics principles will increase the likelihood of recipients of care attending clinic appointments and returning within 28 days of a missed appointment.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of Behaviourally Informed Text Messages to Promote Retention in HIV Care: A Randomized Trial in Ekurhuleni District, South Africa
Govathson C, Pascoe S, Chetty-Makkan C, Schmucker L, et al · · 2023 · DOI 10.1101/2023.10.29.23297725
Verify or expand the search:
- PubMed search for NCT05010291
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05010291 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Pennsylvania
- Last refreshed: 20 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05010291.
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