Who is sponsoring NCT05002829?

NCT05002829 is sponsored by Denver Health and Hospital Authority.

What drugs are being tested in NCT05002829?

Interventions in NCT05002829: Restricted Duration of SOC Antibiotic Use, Liberal Duration of SOC Antibiotic Use.

What condition does NCT05002829 study?

NCT05002829 studies Appendicitis.

Is NCT05002829 still recruiting?

NCT05002829 is currently completed. Last updated 31 October 2025.

Last reviewed 2025-10-31 · How we verify

NCT05002829: CASA RELAX

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Restricted or Liberal Antibiotics After Appendectomy - Denver Health

Completed NA Last updated 31 October 2025

What this trial tests

NA trial testing Restricted Duration of SOC Antibiotic Use in Appendicitis in 657 participants. Completed in 16 July 2025.

Timeline

1 November 2021

Primary endpoint
16 July 2025

16 July 2025

Quick facts

Lead sponsor	Denver Health and Hospital Authority
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	657
Start date	1 November 2021
Primary completion	16 July 2025
Estimated completion	16 July 2025
Sites	1 location across United States

Drugs / interventions tested

Restricted Duration of SOC Antibiotic Use
Liberal Duration of SOC Antibiotic Use

Conditions studied

Appendicitis — all drugs for Appendicitis →

Sponsor

Denver Health and Hospital Authority

Who can join

18 and older, any sex, with Appendicitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to see if decreasing the amount of antibiotics after appendicitis surgery can decrease the risk of adverse effects associated with antibiotics while at the same time ensuring participant safety.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Complex And Simple Appendicitis: REstrictive or Liberal postoperative Antibiotic eXposure (CASA RELAX) using Desirability of Outcome Ranking (DOOR) and Response Adjusted for Duration of Antibiotic Risk (RADAR): study protocol for a randomized controlled trial.
Yeh DD, Hatton GE, Pedroza C, Pust G, et al · · 2022 · cited 2× · PMID 36148315 · DOI 10.1136/tsaco-2022-000931

Verify or expand the search:

Other recruiting trials for Appendicitis

Currently open trials in the same condition.

NCT07115303 — Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump Closure · NA · recruiting
NCT06395636 — Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients · NA · recruiting
NCT07049965 — Comparative Study of Harmonic Scalpel vs. Suture Ligation for Appendix Base During Laparoscopic Appendectomy · NA · active not recruiting
NCT07478029 — Clinical Study of PEG Bowel Preparation in Appendectomy Patients · recruiting
NCT06177418 — Transumbilical Laparoscopic Appendectomy · NA · recruiting

Other Denver Health and Hospital Authority trials

Trials by the same sponsor.

NCT07435662 — Optimizing Heart Failure Therapies Among Patients With Limited Access in Denver · NA · recruiting
NCT06496035 — Blood Flow Restriction Training in Patients With Lower Extremity Fractures · NA · recruiting
NCT06274359 — Digital Storytelling to Reduce Pediatric Influenza Vaccination Disparities · NA · terminated
NCT07223918 — Personalized Decision-Aid to Guide Tracheostomy and Prolonged Mechanical Ventilation Decision-Making · completed
NCT05603481 — CGM in Patients With ED's · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05002829 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Denver Health and Hospital Authority
Last refreshed: 31 October 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05002829.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing