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NCT04999423: SEALANT
LVIS™ Evo™ and HydroCoil® Embolic System for Intracranial Aneurysm Treatment
trial testing LVIS EVO and HydroCoil Embolic System in Intracranial Aneurysm in 206 participants. Participants enrolled and being followed up; not accepting new ones.
1 March 2025
Quick facts
| Lead sponsor | Microvention-Terumo, Inc. |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 206 |
| Start date | 14 January 2022 |
| Primary completion | 1 March 2025 |
| Estimated completion | 1 December 2026 |
| Sites | 19 locations across France, Italy, Belgium, United Kingdom, Germany |
Drugs / interventions tested
- LVIS EVO and HydroCoil Embolic System
Conditions studied
- Intracranial Aneurysm — all drugs for Intracranial Aneurysm →
Sponsor
Microvention-Terumo, Inc. — full company profile →
Who can join
18 and older, any sex, with Intracranial Aneurysm. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a prospective multicenter international single-arm observational study to demonstrate that use of stent-assisted coiling with LVIS™ Evo™ and HydroCoil® Embolic System (HES) in intracranial aneurysm treatment is effective and safe when assessed at 1 year after the procedure
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04999423
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Intracranial Aneurysm
Currently open trials in the same condition.
- NCT07123818 — AI for Detection of Brain Aneurysm: Low-cost Opportunistic Screening · NA · active not recruiting
- NCT06494436 — Microvention AnEurysm & STroke Real-life Data cOllection · recruiting
- NCT06588543 — Patient-specific Planning of Minimally Invasive Brain Interventions Based on Vascular-hemodynamic Mapping · recruiting
- NCT05831202 — SEAL™IT: Saccular Endovascular Aneurysm Lattice System Interventional Pivotal Trial · Phase 3 · active not recruiting
- NCT06416657 — General Anesthesia vs Local Anesthesia for Endovascular Treatment in Patients With Unruptured Intracranial Aneurysm Usin · NA · recruiting
Other Microvention-Terumo, Inc. trials
Trials by the same sponsor.
- NCT06494436 — Microvention AnEurysm & STroke Real-life Data cOllection · recruiting
- NCT06215105 — Complex Aneurysm Registry - Real-World Evidence Data Collection Intracranial Aneurysm Treatment Devices · enrolling by invitation
- NCT05361187 — BOBBY™ Balloon Guide Catheter for Endovascular Treatment of Acute Ischemic Stroke · terminated
- NCT05453240 — Post-Market Surveillance Study to Evaluate the Long-Term Safety and Effectiveness of the LVIS Device · enrolling by invitation
- NCT04451525 — REal-World Analyses of Stroke - Thrombus Occlusion REtrieval · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04999423 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Microvention-Terumo, Inc.
- Last refreshed: 7 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04999423.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing